Universidad Autónoma de Nuevo León, Facultad de Medicina, Servicio de Hematología, Hospital Universitario "Dr. José E. González", Monterrey, Mexico.
Centro de Hematología y Medicina Interna, Clínica RUIZ, Puebla, Mexico.
Hematology. 2022 Dec;27(1):971-976. doi: 10.1080/16078454.2022.2117119.
to discuss the status and challenges associated with the management of acute lymphoblastic leukemia (ALL) in Latin America.
This review summarizes various insights gained from information regarding diagnostic approaches and treatment strategies in adult patients with ALL in Latin American Countries.
Information regarding ALL in Latin America is scarce; however, many efforts have been made to overcomes these barriers. Nevertheless, major obstacles to successful treatment in Latin America and LMIC remain poor adherence, abandonment of treatment, and lack of supportive therapy and new therapeutic agents.
Further improvements in survival should be pursued by developing more Latin American registries, forming cooperative groups, developing educational models to facilitate earlier diagnosis and prevention of complications, better support therapy and management of infections, and adapting treatment strategies.
讨论拉丁美洲急性淋巴细胞白血病（ALL）管理的现状和挑战。
本综述总结了从拉丁美洲国家成人 ALL 患者的诊断方法和治疗策略信息中获得的各种见解。
关于拉丁美洲 ALL 的信息很少，但已经做出了许多努力来克服这些障碍。然而，拉丁美洲和 LMIC 成功治疗的主要障碍仍然是治疗依从性差、放弃治疗以及缺乏支持性治疗和新的治疗药物。
通过开发更多的拉丁美洲登记处、组建合作组、制定促进早期诊断和预防并发症的教育模式、更好地支持治疗和管理感染以及调整治疗策略，应进一步提高生存。
