Tootla Hafsah D, Eley Brian S, Enslin Johannes M N, Frean John A, Hlela Carol, Kilborn Tracy N, Moodley Bhavani, Peer Shazia, Singh Shivani, Nuttall James J C
Division of Medical Microbiology, National Health Laboratory Service (Red Cross War Memorial Children's Hospital) and University of Cape Town, Cape Town, South Africa.
Paediatric Infectious Diseases Unit, Department of Paediatrics and Child Health, University of Cape Town and Red Cross War Memorial Children's Hospital, Cape Town, South Africa.
J Pediatric Infect Dis Soc. 2022 Dec 28;11(12):578-581. doi: 10.1093/jpids/piac096.
We report the first case of Balamuthia mandrillaris granulomatous amoebic encephalitis definitively acquired in Africa. Our case emphasizes initial nonspecific dermatological features, delays in confirmation of the diagnosis, difficulties accessing recommended medication, and uncertainty about optimal treatment of a disease with a frequently fatal outcome.
我们报告了首例在非洲确诊感染的曼氏巴通体肉芽肿性阿米巴脑炎病例。我们的病例强调了最初的非特异性皮肤特征、诊断确认的延迟、获取推荐药物的困难以及对这种通常致命疾病的最佳治疗方法的不确定性。