Department of Ophthalmology.
Department of Radiology, the First Hospital of Jilin University, Changchun, China.
J Craniofac Surg. 2022;33(5):1300-1302. doi: 10.1097/SCS.0000000000008324. Epub 2021 Oct 27.
To report 2 successfully managed cases of graft rejection with acellular porcine corneal stroma (APCS) transplantation in patients with fungal corneal ulcer. Two patients were diagnosed with fungal corneal ulcer and received APCS transplantation. Graft rejection developed due to the lost follow-up during the period of coronavirus disease 2019 outbreak. Amniotic membranes transplantation and cauterization of neovascularization was performed, respectively. The graft failure resolved successfully after the procedure. To the best of our knowledge, amniotic membranes transplantation and cauterization of new vessels are the firstly reported in treating APCS graft failure. Amniotic membranes transplantation or cauterization of neovascularization appear to be a safe and costeffective method for treating graft failure.
报告 2 例成功治疗的真菌性角膜溃疡患者的去细胞猪角膜基质（APCS）移植术后排斥反应。2 例患者均诊断为真菌性角膜溃疡，接受了 APCS 移植。由于在 2019 年冠状病毒病爆发期间失去随访，导致移植物排斥反应。分别进行了羊膜移植和新生血管烧灼。术后移植物失功成功解决。据我们所知，羊膜移植和新生血管烧灼是首次报道用于治疗 APCS 移植物失功。羊膜移植或新生血管烧灼似乎是一种安全且具有成本效益的治疗移植物失功的方法。
