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Intranasal dexmedetomidine is safe for procedural sedation in preterm and neonate infants.

作者信息

Zhou Jieshu, Li Hao, Lin Xuemei

机构信息

Department of Anesthesiology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, Sichuan, China.

Department of Anesthesiology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, Sichuan, China.

出版信息

Asian J Surg. 2023 Mar;46(3):1280-1281. doi: 10.1016/j.asjsur.2022.08.067. Epub 2022 Aug 27.

DOI:10.1016/j.asjsur.2022.08.067
PMID:36041899
Abstract
摘要

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Intranasal dexmedetomidine is safe for procedural sedation in preterm and neonate infants.鼻内给予右美托咪定对早产儿和新生儿进行操作镇静是安全的。
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Analysis of 17 948 pediatric patients undergoing procedural sedation with a combination of intranasal dexmedetomidine and ketamine.对17948例采用鼻内右美托咪定和氯胺酮联合进行程序性镇静的儿科患者的分析。
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Systematic review and meta-analysis found that intranasal dexmedetomidine was a safe and effective sedative drug during paediatric procedural sedation.系统评价和荟萃分析发现，在儿科程序镇静期间，鼻内给予右美托咪定是一种安全有效的镇静药物。
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引用本文的文献

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Intranasal Analgesia in Preterm and Term Neonates.早产和足月新生儿的鼻内镇痛
Paediatr Drugs. 2025 Mar;27(2):191-199. doi: 10.1007/s40272-024-00672-4. Epub 2024 Dec 11.
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Intranasal dexmedetomidine reduces pain scores in preterm infants during retinopathy of prematurity screening.鼻内给予右美托咪定可降低早产儿在早产儿视网膜病变筛查期间的疼痛评分。
Front Pediatr. 2024 Aug 2;12:1441324. doi: 10.3389/fped.2024.1441324. eCollection 2024.