Centre for Vaccinology and Regenerative Medicine, Department of Pathobiology and Population Sciences, Royal Veterinary College, University of London, London, UK.
Division of Infection and Immunity, The Roslin Institute, University of Edinburgh, Edinburgh, UK.
Trends Parasitol. 2022 Nov;38(11):930-932. doi: 10.1016/j.pt.2022.08.006. Epub 2022 Aug 27.
Since its discovery, bovine theileriosis has caused major socioeconomic losses in sub-Saharan Africa. Acaricide resistance of the intermediate host, paucity of therapeutics, and lack of sufficiently cross-protective vaccines increase the risk of parasite spread due to global warming. Here, we highlight three important areas that require investigation to develop next-generation vaccines.
自发现以来，牛泰勒虫病在撒哈拉以南非洲地区造成了重大的社会经济损失。中间宿主的杀螨剂耐药性、治疗方法的缺乏以及缺乏足够的交叉保护疫苗，增加了由于全球变暖导致寄生虫传播的风险。在这里，我们强调了三个需要研究的重要领域，以开发下一代疫苗。
