Suppr超能文献

列线图预测冠状动脉旁路移植术后心房颤动。

Nomogram predicts atrial fibrillation after coronary artery bypass grafting.

机构信息

Department of Cardiovascular Surgery, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, 266003, China.

出版信息

BMC Cardiovasc Disord. 2022 Aug 30;22(1):388. doi: 10.1186/s12872-022-02824-1.

Abstract

OBJECTIVE

Using the nomogram to intuitively predict atrial fibrillation after coronary artery bypass grafting. Identify high-risk patients with atrial fibrillation and provide preoperative protective therapy.

METHODS

A total of 397 patients that underwent coronary artery bypass grafting were consecutively enrolled. Independent predictors of patients were analyzed by multivariate logistic regression. Two nomograms were constructed to predict postoperative atrial fibrillation.

RESULTS

The incidence of postoperative atrial fibrillation in this study was 29% (115/397). Multivariate Logistic showed that Age, Operative Time > 4 h, Left Atrial Diameter > 40 mm, Mean Arterial Pressure, Body Mass Index > 23 kg/m, Insulins, and Statins were independently associated with atrial fibrillation after isolated coronary artery bypass grafting. The nomogram of postoperative atrial fibrillation in patients was constructed using total predictor variables (AUC = 0.727, 95% CI 0.673-0.781). The model was internally validated (AUC = 0.701) by K-fold Cross-validation resampling (K = 5, Times = 400). To make an early intervention, the intraoperative information of the patients was excluded. Only 6 variables before surgery were used to establish the brief nomogram to predict postoperative atrial fibrillation (AUC = 0.707, 95% CI 0.651-0.764). The brief model was internally validated (AUC = 0.683) by resampling with K-fold Cross-validation resampling.

CONCLUSIONS

These two nomograms could be used to predict patients at high risk for atrial fibrillation after isolated coronary artery bypass grafting.

摘要

目的

使用列线图直观预测冠状动脉旁路移植术后心房颤动。识别心房颤动的高危患者并提供术前保护治疗。

方法

连续纳入 397 例接受冠状动脉旁路移植术的患者。采用多变量逻辑回归分析患者的独立预测因素。构建两个列线图预测术后心房颤动。

结果

本研究术后心房颤动发生率为 29%(115/397)。多变量 Logistic 显示,年龄、手术时间>4 小时、左心房直径>40mm、平均动脉压、体质量指数>23kg/m、胰岛素和他汀类药物与单纯冠状动脉旁路移植术后心房颤动独立相关。使用总预测变量构建了患者术后心房颤动的列线图(AUC=0.727,95%CI 0.673-0.781)。通过 K 折交叉验证重采样(K=5,Times=400)对模型进行内部验证(AUC=0.701)。为了进行早期干预,排除了患者的术中信息。仅使用术前的 6 个变量建立了预测术后心房颤动的简要列线图(AUC=0.707,95%CI 0.651-0.764)。通过 K 折交叉验证重采样对简要模型进行内部验证(AUC=0.683)。

结论

这两个列线图可用于预测单纯冠状动脉旁路移植术后心房颤动风险较高的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b42c/9429785/5599d8a7f876/12872_2022_2824_Fig1_HTML.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验