Department of Nursery, Gulin people's Hospital, Sichuan, China.
Medicine (Baltimore). 2022 Aug 26;101(34):e30169. doi: 10.1097/MD.0000000000030169.
To clarify the risk factors for frailty to help doctors prevent diseases that cause weakness, through early interventions.
We searched the PubMed, EMBASE, and Cochrane Library databases to identify all relevant studies using the items "frailty," "weak," "risk factors," and "predictive factors" and compared their results. The aging population (≥65 years old) was divided into 2 groups, a "frailty group" and a "robust control group," and then the characteristics, lifestyles, and comorbidities were compared.
We compared the influence of baseline and concomitant diseases on frailty in the elderly respectively, and the analysis of the influence of baseline on frailty found that increasing age, lower weight, female sex, living alone, low levels of exercise, polypharmacy, higher education level, smoking, drinking, malnutrition, and lower vitamin D levels were associated with aging individuals being more likely to experience frailty. The data about concomitant diseases had shown that diabetes, hearing dysfunction, cognitive impairment, poor sleep, a history of falls, pain, and depression can increase the risk of frailty among the elderly population.
Characteristics, comorbidities, and lifestyle factors can impact the occurrence of frailty, and relevant influencing factors should be considered.
通过早期干预，明确导致虚弱的风险因素，帮助医生预防导致虚弱的疾病。
我们检索了 PubMed、EMBASE 和 Cochrane Library 数据库，使用“虚弱”、“乏力”、“风险因素”和“预测因素”等项目，查找所有相关研究，并比较其结果。将老年人群（≥65 岁）分为 2 组，即“虚弱组”和“健壮对照组”，然后比较其特征、生活方式和合并症。
我们分别比较了基线和合并症对老年人虚弱的影响，对基线影响的分析发现，年龄增长、体重降低、女性、独居、运动水平低、多种药物治疗、较高的教育水平、吸烟、饮酒、营养不良和较低的维生素 D 水平与老年人更容易出现虚弱有关。关于合并症的数据表明，糖尿病、听力障碍、认知障碍、睡眠不佳、跌倒史、疼痛和抑郁会增加老年人群出现虚弱的风险。
特征、合并症和生活方式因素会影响虚弱的发生，应考虑相关的影响因素。
