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胶原酶注射治疗腰椎间盘突出症后髓核迁移的磁共振成像:病例报告

MR Imaging of Migrated Nucleus Pulposus after Collagenase Injection of Lumbar Disc Herniation: A Case Report.

作者信息

Sun Bai Jin Tao, Li Bing, Feng Xu, Yang Han Feng

机构信息

Affiliated Hospital of North Sichuan Medical College, CN.

出版信息

J Belg Soc Radiol. 2022 Aug 11;106(1):73. doi: 10.5334/jbsr.2777. eCollection 2022.

DOI:10.5334/jbsr.2777
PMID:36042789
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9374009/
Abstract

Magnetic resonance images (MRI) of migrated nucleus pulposus after collagenase treatment of lumbar disc herniation are rarely published. Here, we describe a 65-year-old woman with L5-S1 intervertebral disc herniation on the rear left. The patient was treated with a lumbar disc collagenase injection, and the pain was relieved. Two weeks later, the patient suddenly developed pain again after engaging in weight-bearing activity. Lumbar MRI showed a nodule in the spinal canal at the L5-S1 level. The patient underwent surgical treatment two days later. Pathology showed that the nodule was nucleus pulposus tissue. It is important to understanding the MR manifestations of migrated nucleus pulposus after collagenase treatment to prevent such misdiagnosis.

摘要

胶原酶治疗腰椎间盘突出症后髓核迁移的磁共振成像(MRI)报道很少。在此,我们描述一位65岁女性,其左后方存在L5-S1椎间盘突出症。该患者接受了腰椎间盘胶原酶注射治疗,疼痛得到缓解。两周后,患者在进行负重活动后突然再次出现疼痛。腰椎MRI显示L5-S1水平椎管内有一个结节。两天后患者接受了手术治疗。病理显示该结节为髓核组织。了解胶原酶治疗后髓核迁移的磁共振表现对于预防此类误诊很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/825a/9374009/4b2b41c97d90/jbsr-106-1-2777-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/825a/9374009/9d6b0347a4e9/jbsr-106-1-2777-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/825a/9374009/8fcc08966efe/jbsr-106-1-2777-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/825a/9374009/65dd607fee3b/jbsr-106-1-2777-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/825a/9374009/4b2b41c97d90/jbsr-106-1-2777-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/825a/9374009/9d6b0347a4e9/jbsr-106-1-2777-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/825a/9374009/8fcc08966efe/jbsr-106-1-2777-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/825a/9374009/65dd607fee3b/jbsr-106-1-2777-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/825a/9374009/4b2b41c97d90/jbsr-106-1-2777-g4.jpg

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本文引用的文献

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Chemonucleolysis with chondroitin sulfate ABC endolyase as a novel minimally invasive treatment for patients with lumbar intervertebral disc herniation.硫酸软骨素ABC内切酶化学髓核溶解术作为腰椎间盘突出症患者的一种新型微创治疗方法。
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Injectable hydrogel provides growth-permissive environment for human nucleus pulposus cells.可注射水凝胶为人类髓核细胞提供有利于生长的环境。
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Target radiofrequency combined with collagenase chemonucleolysis in the treatment of lumbar intervertebral disc herniation.
靶点射频联合胶原酶化学溶解术治疗腰椎间盘突出症
Int J Clin Exp Med. 2015 Jan 15;8(1):526-32. eCollection 2015.
4
Percutaneous treatment of non-contained lumbar disc herniation by injection of oxygen-ozone combined with collagenase.经皮注射臭氧-胶原酶治疗非包容型腰椎间盘突出症。
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Nomenclature and classification of lumbar disc pathology.腰椎间盘病变的命名与分类
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