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腮腺硬化性多囊性腺病伴牙关紧闭:一例报告及文献复习

Sclerosing polycystic adenosis arising in the parotid gland with trismus: a case report and literature review.

作者信息

Yee Young-Jae, Han Dawool, Lee Chena, Kim Jun-Young

机构信息

Department of Oral and Maxillofacial surgery, Oral Science Research Center, Yonsei University College of Dentistry, Seoul, Korea.

Department of Oral Pathology, Oral Cancer Research Institute, Yonsei University College of Dentistry, Seoul, Korea.

出版信息

J Korean Assoc Oral Maxillofac Surg. 2022 Aug 31;48(4):237-241. doi: 10.5125/jkaoms.2022.48.4.237.

DOI:10.5125/jkaoms.2022.48.4.237
PMID:36043255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9433854/
Abstract

Sclerosing polycystic adenosis (SPA) is a rare, asymptomatic disease that occurs mainly in the salivary glands. We report the case of a 51-year-old man who presented with trismus and pain upon mouth opening. Magnetic resonance imaging revealed a 2-cm mass located in the anterior portion of the left parotid gland. SPA was diagnosed based on histopathological examination of the surgical specimen. In pathologic findings, there was a well-circumscribed multicystic nodule in the parenchyma. Dense fibrosis and chronic non-specific inflammatory cells were observed in the stroma. In 13 previous reports on SPA, the most preferred treatment was superficial or total parotidectomy. This report suggests that simple excision of SPA preserves facial nerve function and facial volume.

摘要

硬化性多囊性腺病(SPA)是一种罕见的无症状疾病,主要发生于唾液腺。我们报告一例51岁男性患者,其表现为牙关紧闭及张口时疼痛。磁共振成像显示左腮腺前部有一个2厘米大小的肿块。根据手术标本的组织病理学检查诊断为SPA。病理检查发现,实质内有一个边界清楚的多囊性结节。间质中可见致密纤维化及慢性非特异性炎性细胞。在之前13篇关于SPA的报道中,最常用的治疗方法是腮腺浅叶切除术或全腮腺切除术。本报告提示,单纯切除SPA可保留面神经功能及面部容积。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4a/9433854/7d4e348dacd8/jkaoms-48-4-237-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4a/9433854/f2cee3cd0c9d/jkaoms-48-4-237-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4a/9433854/7d4e348dacd8/jkaoms-48-4-237-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4a/9433854/f2cee3cd0c9d/jkaoms-48-4-237-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4a/9433854/7d4e348dacd8/jkaoms-48-4-237-f2.jpg

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本文引用的文献

1
Coexistence of sclerosing polycystic adenosis and dysgenetic polycystic disease of parotid, Report of a case.硬化性多囊性腺病与腮腺发育异常性多囊病并存:一例报告
Indian J Pathol Microbiol. 2020 Jan-Mar;63(1):109-111. doi: 10.4103/IJPM.IJPM_502_18.
2
Sclerosing Polycystic "Adenosis" of Salivary Glands: A Neoplasm Characterized by PI3K Pathway Alterations More Correctly Named Sclerosing Polycystic Adenoma.唾液腺硬化性多囊“腺瘤病”:一种以 PI3K 通路改变为特征的肿瘤,更名为硬化性多囊性腺瘤。
Head Neck Pathol. 2020 Sep;14(3):630-636. doi: 10.1007/s12105-019-01088-0. Epub 2019 Oct 11.
3
Juvenile sclerosing polycystic adenosis cytologically mimicking Warthin tumor.
细胞学上酷似沃辛瘤的青少年硬化性多囊性腺病
Diagn Cytopathol. 2019 Nov;47(11):1208-1212. doi: 10.1002/dc.24283. Epub 2019 Jul 22.
4
WHO is in and WHO is out of the mouth, salivary glands, and jaws sections of the 4th edition of the WHO classification of head and neck tumours.在《世界卫生组织头颈部肿瘤分类》第4版中,口腔、唾液腺及颌部章节所涵盖和未涵盖的内容。
Br J Oral Maxillofac Surg. 2018 Feb;56(2):90-95. doi: 10.1016/j.bjoms.2017.12.009. Epub 2018 Jan 17.
5
Sclerosing Polycystic Adenosis of the Parotid Gland: A Systematic Review and Report of 2 New Cases.
J Oral Maxillofac Surg. 2017 May;75(5):984-993. doi: 10.1016/j.joms.2016.10.031. Epub 2016 Nov 2.
6
Surgical Treatment of Rare Sclerosing Polycystic Adenosis of the Deep Parotid Gland.腮腺深部罕见硬化性多囊性腺病的外科治疗
Plast Reconstr Surg Glob Open. 2016 Mar 17;4(3):e645. doi: 10.1097/GOX.0000000000000614. eCollection 2016 Mar.
7
Sclerosing Polycystic Adenosis: A Rare Tumor of the Salivary Glands.硬化性多囊性腺病:一种罕见的唾液腺肿瘤。
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