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减重和代谢手术对 COVID-19 大流行期间感染患者发病率和死亡率的影响:一项回顾性队列研究。

The impact of bariatric and metabolic surgery on the morbidity and mortality of patients infected during the COVID-19 pandemic: a retrospective cohort study.

机构信息

MD. Physician and General Surgeon, Postgraduate Program in Digestive Tract Surgery, Colégio Brasileiro de Cirurgia Digestiva (CBCD), Aracaju (SE), Brazil.

Undergraduate Student of Medical Sciences, Faculdade de Medicina-Universidade Cidade de São Paulo (FM-UNICID), São Paulo (SP), Brazil.

出版信息

Sao Paulo Med J. 2022 Aug 29;141(2):120-124. doi: 10.1590/1516-3180.2021.0952.R2.11052022. eCollection 2022.

Abstract

BACKGROUND

Since the impact of the coronavirus disease 2019 (COVID-19) pandemic in March 2020, several studies have shown a strong relationship between obesity and severe cases of COVID-19. It is imperative to assess whether bariatric surgery exerts a protective effect in such cases.

OBJECTIVE

This study aimed to assess the impact of bariatric surgery on the morbidity and mortality in obese patients during the COVID-19 pandemic. A comprehensive search was performed using the PubMed and Cochrane Library databases.

DESIGN AND SETTING

Retrospective cohort studies conducted in the Faculdade de Medicina da Universidade Cidade de São Paulo, São Paulo (SP), Brazil.

METHODS

The search comprised the following descriptors: "bariatric, surgery, COVID-19". Current retrospective cohort studies that examined the influence of bariatric surgery on the morbidity and mortality of obese patients during the COVID-19 pandemic were considered eligible.

RESULTS

After removing duplicates, 184 studies were obtained from the databases. Of these, 181 were excluded from the analysis as they did not meet the eligibility criteria. Patients undergoing postoperative follow-up of bariatric surgery had a similar probability of SARS-CoV-2 infection compared to the general population, and persistent comorbidities were associated with an increased risk and severity of infection.

CONCLUSION

Bariatric surgery has a protective effect against severe COVID-19 in the obese population, bringing the prevalence of severe disease cases to levels equivalent to those of the nonobese general population, with a positive impact on morbidity and mortality.

摘要

背景

自 2020 年 3 月冠状病毒病 2019(COVID-19)大流行以来,多项研究表明肥胖与 COVID-19 重症病例之间存在很强的关联。评估减重手术在此类病例中是否具有保护作用至关重要。

目的

本研究旨在评估 COVID-19 大流行期间减重手术对肥胖患者发病率和死亡率的影响。使用 PubMed 和 Cochrane Library 数据库进行了全面检索。

设计和设置

巴西圣保罗市城市大学医学院进行的回顾性队列研究。

方法

检索词包括“bariatric、surgery、COVID-19”。纳入的研究为评估 COVID-19 大流行期间减重手术对肥胖患者发病率和死亡率影响的回顾性队列研究。

结果

从数据库中去除重复项后,获得了 184 项研究。其中,181 项因不符合纳入标准而被排除在分析之外。接受减重手术后随访的患者与普通人群相比,感染 SARS-CoV-2 的概率相似,持续存在的合并症与感染风险和严重程度增加相关。

结论

减重手术对肥胖人群的严重 COVID-19 具有保护作用,将严重疾病病例的发生率降低到与非肥胖普通人群相当的水平,对发病率和死亡率产生积极影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad54/10005465/6552e3e37816/1806-9460-spmj-1516-3180-2021-0952-R2-11052022-gf01.jpg

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