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用阿苯达唑治疗粪类圆线虫。治愈率为86%。

Treatment of strongyloides stercoralis with albendazole. A cure rate of 86 per cent.

作者信息

Mojon M, Nielsen P B

出版信息

Zentralbl Bakteriol Mikrobiol Hyg A. 1987 Mar;263(4):619-24. doi: 10.1016/s0176-6724(87)80208-0.

Abstract

A clinical trial concerning the efficacy of albendazole has been performed in an area outside the endemic zone. Sixty-eight patients were treated with albendazole in doses varying from 4-30 mg/kg/day for 3-6 days. A high cure rate of 86 per cent was obtained with albendazole 16 mg/kg/day for three days and repeated once after a fortnight. The albendazole was well tolerated and no side effects were imputed to the treatment. Successful treatment was confirmed by seven negative, consecutive coprocultures. The follow up period ranged from 35 to 615 days.

摘要

在非流行区的一个地区进行了一项关于阿苯达唑疗效的临床试验。68名患者接受了阿苯达唑治疗,剂量为4 - 30毫克/千克/天,持续3 - 6天。采用16毫克/千克/天的阿苯达唑治疗三天,两周后重复一次,治愈率高达86%。阿苯达唑耐受性良好,未发现该治疗有副作用。连续七次粪便培养阴性证实治疗成功。随访期为35至615天。

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