Vasil'eva V I, Prozorovskiĭ S V, Rusakova E V, Tartakovskiĭ I S, Kazakov M A
Zh Mikrobiol Epidemiol Immunobiol. 1987 Apr(4):44-7.
In this work the immune structure of an organized group with respect to acute respiratory infections and the etiological structure of cases of acute pneumonia was studied. The sera taken from 602 persons were tested for the presence of antibodies to 14 infective agents of the viral, bacterial and mycoplasmal nature. The data indicate that all these agents circulate in the group under study with the prevalence of influenza A (H3N2), influenza B and group III parainfluenza viruses. Among etiological agents of acute pneumonia, the combination of Staphylococcus with Mycoplasma pneumoniae and adenovirus was noted. The Legionella etiology of some group cases of acute pneumonia among young persons was established on the basis of the increased titers of L. pneumophila antibodies in the indirect hemagglutination, indirect immunofluorescence and enzyme immunoassay. The source of this infection was highly dispersed water aerosol, containing the infective agent, in shower baths. This was bacteriologically confirmed by the isolation of three Legionella strains. The study showed that no transfer of Legionella infection in the group through contacts was possible.
在这项工作中,研究了一个有组织群体针对急性呼吸道感染的免疫结构以及急性肺炎病例的病因结构。对从602人采集的血清进行检测,以确定是否存在针对14种病毒、细菌和支原体性质感染因子的抗体。数据表明,所有这些病原体在研究群体中传播,其中甲型流感(H3N2)、乙型流感和III型副流感病毒最为常见。在急性肺炎的病原体中,注意到金黄色葡萄球菌与肺炎支原体和腺病毒的组合。基于间接血凝、间接免疫荧光和酶免疫测定中嗜肺军团菌抗体滴度升高,确定了一些年轻人群急性肺炎群体病例的军团菌病因。这种感染源是淋浴喷头中高度分散的含有感染因子的水气溶胶。通过分离出三株军团菌菌株,从细菌学上证实了这一点。研究表明,该群体中军团菌感染不可能通过接触传播。