Bhattarai Himal Bikram, Yadav Rukesh, Shah Sangam, Uprety Manish, Subedi Ayusha, Singh Prabesh Bikram, Devkota Anirudra, Panthi Niranjan
Gandaki Medical College, Pokhara, Nepal.
Tribhuvan University, Institute of Medicine, Maharajgunj, 44600, Nepal.
Ann Med Surg (Lond). 2022 Jul 15;80:104208. doi: 10.1016/j.amsu.2022.104208. eCollection 2022 Aug.
Parotid fistula is an uncommon consequence of surgical or non-surgical trauma to the parotid gland or the area surrounding it. To treat it, a variety of pharmacological medicines and surgical techniques are used, each with their own set of benefits, drawbacks, and patient preferences.
We present the successful care of a young female with post-traumatic parotid fistula using hypertonic saline injections into the parotid substance, which is a simple yet efficient approach of treating this abnormality.
Thermodynamic and physicochemical calculations suggest that hypertonic saline solutions work to close parotid fistula by causing conformational denaturation of the cell membrane proteins in situ and saline can be diluted to a point where there will be no cellular toxicity. It is advised that temperature of the saline should be raised above body temperature to enhance the fibrosing property of physiologic saline.
The use of hypertonic hot saline injections combined with compression dressing is a cost-effective, patient-friendly, and almost complication-free approach of treating parotid fistulas with promising results.
腮腺瘘是腮腺或其周围区域遭受手术或非手术创伤后罕见的后果。为了治疗它，人们使用了各种药物和手术技术，每种方法都有其自身的一系列优点、缺点以及患者偏好。
我们展示了对一名患有创伤后腮腺瘘的年轻女性的成功治疗，方法是向腮腺实质内注射高渗盐水，这是一种治疗这种异常情况的简单而有效的方法。
热力学和物理化学计算表明，高渗盐溶液通过使细胞膜蛋白原位构象变性来闭合腮腺瘘，并且盐水可以稀释到不会产生细胞毒性的程度。建议将盐水温度升高至体温以上，以增强生理盐水的纤维化特性。
使用高渗热盐水注射联合压迫敷料是一种经济有效、对患者友好且几乎无并发症的治疗腮腺瘘的方法，效果良好。
