Ton Gil, Lin Chia-Hui, Ho Wen-Chao, Lai Wan-Yu, Yen Hung-Rong, Lee Yu-Chen
College of Chinese Medicine, Graduate Institute of Acupuncture Science, China Medical University, Taichung, Taiwan.
Department of Acupuncture, China Medical University Hospital, Taichung, Taiwan.
Med Acupunct. 2022 Aug 1;34(4):228-239. doi: 10.1089/acu.2022.0002. Epub 2022 Aug 17.
Nocturnal enuresis (NE), often known as bedwetting, is a common condition in children and, as a result, they may have subsequent social impairments. The aim of this study was to evaluate the efficacy of low-level laser therapy (LLLT) in children with NE.
International databases with laser- and NE-related keywords were searched, and only randomized controlled trials (RCTs) that used any type of LLLT to treat NE and compared it with any type of control intervention were included. Eleven studies using laser acupuncture therapy (LAT), involving 927 participants, were included for a systematic review. A meta-analysis was conducted using full and partial response-rate variables. The analysis was performed using referred eporting tems for ystematic reviews and eta-nalyses guidelines, and the Cochrane risk-of-bias tool and rading of ecommendations ssessment evelopment and valuation recommendations for quality of evidence were used to rate all included publications.
The LAT groups showed significant improvement, compared with control groups when full response rates were analyzed. There was no significant difference between the groups treated with LAT and the groups who underwent medication therapy alone when full response rates were analyzed. Red and infrared wavelengths and continuous waves were the most commonly used LAT modalities, and lower abdomen and back acupoints were the most-common sites.
LAT seems to be an effective and safe treatment for NE; however, the quality of evidence available in the literature was relatively low. More-rigorous and higher-quality trials are needed to investigate this treatment modality further.
夜间遗尿症（NE），通常被称为尿床，是儿童中的常见病症，因此，患儿可能会有后续的社交障碍。本研究的目的是评估低强度激光疗法（LLLT）对患有NE的儿童的疗效。
检索了包含激光和NE相关关键词的国际数据库，仅纳入使用任何类型的LLLT治疗NE并将其与任何类型的对照干预进行比较的随机对照试验（RCT）。纳入了11项使用激光针刺疗法（LAT）的研究，涉及927名参与者，进行系统评价。使用完全缓解率和部分缓解率变量进行荟萃分析。分析按照系统评价和荟萃分析的报告条目进行，使用Cochrane偏倚风险工具以及证据质量的推荐分级评估发展和评价建议对所有纳入的出版物进行评分。
在分析完全缓解率时，与对照组相比，LAT组有显著改善。在分析完全缓解率时，接受LAT治疗的组与仅接受药物治疗的组之间没有显著差异。红色和红外波长以及连续波是最常用的LAT模式，下腹部和背部穴位是最常见的部位。
LAT似乎是一种治疗NE的有效且安全的方法；然而，文献中现有证据的质量相对较低。需要更严格和更高质量的试验来进一步研究这种治疗方式。
