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术前阿苯达唑治疗对同时患有肝和股外侧肌囊性棘球蚴病患者肌内囊肿结构的影响

The Effect of Preoperative Albendazole Treatment on Intramuscular Cyst Structure in a Patient with Simultaneous Cystic Echinococcusis of Liver and Vastus Lateralis Muscle.

作者信息

Ozsahin Mahmut Kursat, Karaismailoglu Bedri, Davulcu Cumhur Deniz, Sahin Erdem, Hız Murat

机构信息

Orthopaedics and Traumatology Department, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey.

出版信息

Iran J Parasitol. 2022 Jan-Mar;17(1):96-100. doi: 10.18502/ijpa.v17i1.9030.

Abstract

We report a 44-years-old woman with cystic echinococcosis (CE) who presented with simultaneous involvement of liver and vastus lateralis muscle to Istanbul University-Cerrahpasa, Istanbul, Turkey in 2020. Although she underwent surgery for the liver, the intramuscular mass was ignored. While the patient was under post-operative albendazole treatment, she was investigated for the mass on her right thigh which was excised later. The comparison of magnetic resonance imaging before and after albendazole treatment showed that albendazole eliminated the intramuscular vesicle structures by accelerating the degeneration process of the cyst. The comparison of pathology samples sent from both liver and intramuscular CE also revealed that the albendazole has left the laminar membrane intact, degenerate the germinative membrane, thereby reducing the intra-vesicle pressure and also caused the scolex structures to disappear. To the best of our knowledge, this is the first paper to report the effect of preoperative albendazole treatment on the structure of intramuscular CE.

摘要

我们报告了一名44岁患有囊性棘球蚴病(CE)的女性,她于2020年因肝脏和股外侧肌同时受累就诊于土耳其伊斯坦布尔的伊斯坦布尔大学-塞拉哈帕夏医院。尽管她接受了肝脏手术,但肌肉内肿块被忽略了。在患者接受术后阿苯达唑治疗期间,对其右大腿上的肿块进行了检查,该肿块后来被切除。阿苯达唑治疗前后的磁共振成像比较显示,阿苯达唑通过加速囊肿的退变过程消除了肌肉内的囊泡结构。来自肝脏和肌肉内CE的病理样本比较还显示,阿苯达唑使层状膜保持完整,使生发膜退变,从而降低囊内压力,并导致头节结构消失。据我们所知,这是第一篇报道术前阿苯达唑治疗对肌肉内CE结构影响的论文。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75c9/9375718/8be1504579be/IJPA-17-96-g001.jpg

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