Horigome Akihisa, Yamanaka Junko, Takasago Satoshi, Iwamoto Noriko, Saito Tomoya, Shichino Hiroyuki
Department of Pediatrics, National Center for Global Health and Medicine, Japan.
Disease Control and Prevention Center, National Center for Global Health and Medicine, Japan.
Jpn J Infect Dis. 2023 Jan 24;76(1):69-71. doi: 10.7883/yoken.JJID.2021.896. Epub 2022 Aug 31.
We report the first pediatric patient infected with the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Japan. The patient was a one-year-old boy who resided in Japan. He went abroad with his parents from November 12, 2021 to November 28, 2021 and had no known contact with coronavirus disease (COVID-19) patients there. Upon arrival at the Narita International Airport on November 28, 2021, his father tested positive for SARS-CoV-2 via a quantitative antigen test. Because the boy and his mother tested negative for SARS-CoV-2, they quarantined together at a hotel separately from his father. On December 4, 2021, the boy tested positive by reverse-transcription polymerase chain reaction (RT-PCR) for SARS-CoV-2, without symptoms, and was hospitalized with his mother; he and his father were both found to be infected with the SARS-CoV-2 Omicron variant. The boy was not vaccinated against COVID-19. RT-PCR results were negative starting on December 20, 2021. The incubation period and required period for negative conversion of SARS-CoV-2 RNA of the Omicron variant case were similar to those of the cases of conventional strains. We should carefully consider the potential of the SARS-CoV-2 Omicron variant to spread widely among unvaccinated children.
我们报告了日本首例感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)奥密克戎变异株的儿科患者。该患者是一名居住在日本的一岁男童。他于2021年11月12日至2021年11月28日与父母一同出国,在当地没有已知的与冠状病毒病(COVID-19)患者的接触史。2021年11月28日抵达成田国际机场时,他的父亲通过定量抗原检测SARS-CoV-2呈阳性。由于该男童及其母亲的SARS-CoV-2检测结果为阴性,他们与父亲分开在一家酒店进行隔离。2021年12月4日,该男童通过逆转录聚合酶链反应(RT-PCR)检测出SARS-CoV-2呈阳性,且无症状,并与其母亲一同住院;他和他的父亲均被发现感染了SARS-CoV-2奥密克戎变异株。该男童未接种COVID-19疫苗。从2021年12月20日起,RT-PCR结果呈阴性。奥密克戎变异株病例的SARS-CoV-2 RNA潜伏期和转阴所需时间与传统毒株病例相似。我们应仔细考虑SARS-CoV-2奥密克戎变异株在未接种疫苗的儿童中广泛传播的可能性。