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[产科临床环境中新型冠状病毒2019感染的复杂性——基于病例研究的讨论]

[The Complexity of SARS-CoV-2 Infection in the Clinical Setting of Obstetrics - Discussion Based on a Case Study].

作者信息

Möginger Michaela, Mand Nadine, Schoner Katharina, Seipelt Maria, Schulze Maximilian, Köhler Siegmund, Axt-Fliedner Roland, Keil Corinna Nora

机构信息

Universitätsklinikum Gießen und Marburg, Standort Marburg, Klinik für Gynäkologie und Geburtshilfe, Abt. für Geburtshilfe und Perinatologie, Marburg.

Universitätsklinikum Gießen und Marburg, Standort Marburg, Zentrum für Kinder- und Jugendmedizin, Marburg.

出版信息

Z Geburtshilfe Neonatol. 2022 Dec;226(6):416-421. doi: 10.1055/a-1906-1937. Epub 2022 Sep 1.

Abstract

Since the beginning of the pandemic, SARS-CoV-2 infection has dominated clinical practice. In the treatment of high-risk populations, there has long been uncertainty about the extent and consequences of infection. This high-risk population includes pregnant patients. The establishment of clinical registry studies was able to contribute an assessment of the pandemic situation for this collective within a very short time and with enormous effort. Based on a clinical case, the following report describes the association between SARS-CoV-2 infection of a pregnant patient with clinical signs of preeclampsia to the development of posterior reversible encephalopathy syndrome (PRES). Based on the case, the differential diagnostic workup between fulminant course of infection and preeclampsia is presented. The article presents the current data on the occurrence of PRES in pregnancy in the context of SARS-CoV-2 infection and addresses possible differential diagnoses. Interdisciplinary care of the patient allows an overview of aspects of each specialty to be presented.

摘要

自疫情开始以来,新型冠状病毒2型(SARS-CoV-2)感染一直主导着临床实践。在高危人群的治疗中,长期以来,感染的程度和后果一直存在不确定性。这一高危人群包括孕妇。临床登记研究的建立能够在极短时间内并付出巨大努力为这一群体的疫情情况做出评估。基于一个临床病例,以下报告描述了一名感染SARS-CoV-2的孕妇出现先兆子痫临床症状与后部可逆性脑病综合征(PRES)发生之间的关联。基于该病例,介绍了暴发性感染病程与先兆子痫之间的鉴别诊断检查。本文介绍了SARS-CoV-2感染背景下孕期PRES发生的当前数据,并探讨了可能的鉴别诊断。对该患者的多学科护理能够展示各专业方面的概况。

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