Servicio de Nefrología, Hospital Universitario de Salamanca, Salamanca, España.
Hipertens Riesgo Vasc. 2023 Apr-Jun;40(2):98-103. doi: 10.1016/j.hipert.2022.07.004. Epub 2022 Aug 30.
Nephroangiosclerosis or kidney disease that accompanies chronic essential arterial hypertension has been known for more than a hundred years. The definitive diagnosis is established by renal biopsy, which is reserved for doubtful cases or atypical presentation, being in most cases a presumptive clinical diagnosis. The objective of this review is to analyse the main controversies that currently exist related to nephroangiosclerosis: inaccuracy in epidemiological aspects (prevalence and incidence unknown), diagnostic difficulties and lack of correlation studies between clinical data and histopathology, progression factors in Caucasians. Currently, with advances in genetic studies in hypertension, not using or redefining the term hypertensive kidney disease for another condition such as nephropathy related to the present genetic alteration is being considered.
肾血管性硬化症或伴随慢性特发性动脉高血压的肾脏疾病已经有一百多年的历史了。明确的诊断是通过肾活检确定的，这种方法仅用于可疑病例或不典型表现，在大多数情况下，这是一种推测性的临床诊断。本综述的目的是分析目前与肾血管性硬化症相关的主要争议：在流行病学方面（患病率和发病率未知）存在不准确性，诊断困难，以及临床数据与组织病理学之间缺乏相关性研究，白种人进展因素。目前，随着高血压遗传研究的进展，有人认为不使用或重新定义术语“高血压性肾脏病”，而是用与目前遗传改变相关的另一种疾病，如肾病来代替它。
