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经尿道前列腺柱状球囊扩张术前后良性前列腺增生患者的泌尿及性功能变化

Urinary and sexual function changes in benign prostatic hyperplasia patients before and after transurethral columnar balloon dilatation of the prostate.

作者信息

Zhang Dong-Peng, Pan Zheng-Bo, Zhang Hai-Tao

机构信息

Department of Urology, Tianjin Hospital, Tianjin 300211, China.

Department of Urology, Taizhou Municipal Hospital, Taizhou 318000, Zhejiang Province, China.

出版信息

World J Clin Cases. 2022 Jul 16;10(20):6794-6802. doi: 10.12998/wjcc.v10.i20.6794.

Abstract

BACKGROUND

Transurethral columnar balloon dilatation of the prostate (TUCBDP) is a new surgical treatment, but its efficacy remains controversial because of limited clinical application.

AIM

To investigate the clinical effect of TUCBDP for benign prostatic hyperplasia (BPH).

METHODS

Overall, 140 patients with BPH who underwent surgical treatment were included in the study. A random number table was used to divide the participants into study and control groups ( = 70 per group). The study group underwent TUCBDP. The prostate resection surgical time, intraoperative blood loss, bladder irrigation time, catheter indwelling time, length of hospital stay, International Prostate Symptom Score (IPSS), maximum urine flow rate (Qmax), residual urine volume (RUV), changes in the International Erectile Function Score (IIEF-5) score, serum prostate-specific antigen (PSA), quality of life (QOL) score, and surgical complications were compared in both groups.

RESULTS

The operation time, intraoperative blood loss volume, bladder flushing time, urinary catheter indwelling time, and length of hospital stay were significantly lower in the study group than in the control group ( < 0.05). There were no significant differences in the IPSS, Qmax, and RUV measurements between the study and control groups ( > 0.05). However, at 3 mo post-surgery, the IPSS and RUV measurements were both lower ( < 0.05) and Qmax values were higher ( < 0.05) compared to the pre-surgery results in both groups. The IIEF-5 scores before and 3 mo after surgery were not significantly different between the study and control groups ( > 0.05). At 1 mo after surgery, the IIEF-5 score was higher in the study group than in the control group ( < 0.05). The serum PSA levels and QOL scores before treatment and at 1 and 3 mo after treatment were not significantly different between the study and control groups ( > 0.05). However, lower serum PSA levels and QOL scores were observed after 1 and 3 mo of treatment compared to pre-treatment levels in the study group ( < 0.05). The surgical complication rate of the study group (4.29%) was lower than that of the control group (12.86%; < 0.05).

CONCLUSION

TUCBDP for BPH and transurethral resection of the prostate can achieve better results, but the former method is associated with less surgical trauma.

摘要

背景

经尿道柱状气囊前列腺扩张术(TUCBDP)是一种新的外科治疗方法,但由于临床应用有限,其疗效仍存在争议。

目的

探讨经尿道柱状气囊前列腺扩张术治疗良性前列腺增生(BPH)的临床效果。

方法

本研究共纳入140例行手术治疗的BPH患者。采用随机数字表法将参与者分为研究组和对照组(每组 = 70例)。研究组接受经尿道柱状气囊前列腺扩张术。比较两组患者的前列腺切除手术时间、术中出血量、膀胱冲洗时间、导尿管留置时间、住院时间、国际前列腺症状评分(IPSS)、最大尿流率(Qmax)、残余尿量(RUV)、国际勃起功能评分(IIEF - 5)得分变化、血清前列腺特异性抗原(PSA)、生活质量(QOL)评分及手术并发症。

结果

研究组的手术时间、术中出血量、膀胱冲洗时间、导尿管留置时间及住院时间均显著低于对照组(<0.05)。研究组与对照组的IPSS、Qmax及RUV测量值无显著差异(>0.05)。然而,术后3个月时,两组的IPSS和RUV测量值均低于术前(<0.05),Qmax值高于术前(<0.05)。研究组与对照组术前及术后3个月的IIEF - 5得分无显著差异(>0.05)。术后1个月时,研究组的IIEF - 5得分高于对照组(<0.05)。研究组与对照组治疗前及治疗后1个月和3个月的血清PSA水平及QOL评分无显著差异(>0.05)。然而,研究组治疗1个月和3个月后的血清PSA水平及QOL评分低于治疗前水平(<0.05)。研究组的手术并发症发生率(4.29%)低于对照组(12.86%;<0.05)。

结论

经尿道柱状气囊前列腺扩张术治疗BPH与经尿道前列腺切除术均可取得较好效果,但前者手术创伤较小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/972b/9297432/8625d8aba612/WJCC-10-6794-g001.jpg

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