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左侧肋骨孤立性浆细胞瘤误诊为心绞痛:一例报告

Solitary plasmacytoma of the left rib misdiagnosed as angina pectoris: A case report.

作者信息

Yao Jian, He Xu, Wang Cheng-Yuan, Hao Li, Tan Li-Li, Shen Chun-Jian, Hou Ming-Xiao

机构信息

Department of Cardiothoracic Surgery, Second Affiliated Hospital of Shenyang Medical College, The Veterans General Hospital of Liaoning Province, Shenyang 110001, Liaoning Province, China.

Department of Pathology, Second Affiliated Hospital of Shenyang Medical College, the Veterans General Hospital of Liaoning Province, Shenyang 110001, Liaoning Province, China.

出版信息

World J Clin Cases. 2022 Jul 16;10(20):7037-7044. doi: 10.12998/wjcc.v10.i20.7037.

DOI:10.12998/wjcc.v10.i20.7037
PMID:36051148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9297416/
Abstract

BACKGROUND

Solitary plasmacytoma in the left rib is rare and can cause chest discomfort such as chest pain and tightness, and its clinical manifestations are not typical, so it is often misdiagnosed. We report a case of left costal plasmacytoma misdiagnosed as angina pectoris. We also review the literature and provide suggestions as to how to avoid misdiagnosis.

CASE SUMMARY

A 77-year-old man with a history of intermittent chest tightness for 3 years presented with pain in the left chest for 1 wk and was admitted to hospital. The cardiologists initially diagnosed angina pectoris but the findings of coronary angiography were not consistent with the symptoms. Computed tomography showed that the left eighth rib mass was accompanied by bone destruction. The patient was transferred to our department for further treatment. Preoperative biopsy indicated that the lesion was possibly malignant, and elective surgery was performed to remove the lesion. The size of the tumor was about 4 cm. The tumor was spindle-shaped and protruded into the pleural cavity, without invading the lungs. Postoperative pathology confirmed that the left rib lesion was plasmacytoma. After 14 mo follow-up, the patient died of systemic metastasis.

CONCLUSION

Left rib solitary plasmacytoma is a rare disease confined to a specific rib and can cause local pain. Attention should be paid to the differential diagnosis of angina pectoris to avoid misdiagnosis.

摘要

背景

左肋骨孤立性浆细胞瘤罕见,可引起胸痛、胸闷等胸部不适,临床表现不典型,常易误诊。我们报告1例被误诊为心绞痛的左肋骨浆细胞瘤病例。我们还复习了文献,并就如何避免误诊提供建议。

病例摘要

一名77岁男性,有3年间歇性胸闷病史,因左胸痛1周入院。心脏病专家最初诊断为心绞痛,但冠状动脉造影结果与症状不符。计算机断层扫描显示左第八肋骨肿块伴有骨质破坏。患者转入我科进一步治疗。术前活检表明病变可能为恶性,遂行择期手术切除病变。肿瘤大小约4cm。肿瘤呈纺锤形,突入胸腔,未侵犯肺部。术后病理证实左肋骨病变为浆细胞瘤。随访14个月后,患者死于全身转移。

结论

左肋骨孤立性浆细胞瘤是一种局限于特定肋骨的罕见疾病,可引起局部疼痛。应注意与心绞痛进行鉴别诊断,以避免误诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbe/9297416/7892a0ac8975/WJCC-10-7037-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbe/9297416/dc967d5eb556/WJCC-10-7037-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbe/9297416/7dec35677e26/WJCC-10-7037-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbe/9297416/79d1bd4e7a75/WJCC-10-7037-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbe/9297416/0e0dbbb7d487/WJCC-10-7037-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbe/9297416/7892a0ac8975/WJCC-10-7037-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbe/9297416/dc967d5eb556/WJCC-10-7037-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbe/9297416/7dec35677e26/WJCC-10-7037-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbe/9297416/79d1bd4e7a75/WJCC-10-7037-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbe/9297416/0e0dbbb7d487/WJCC-10-7037-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbe/9297416/7892a0ac8975/WJCC-10-7037-g005.jpg

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Rib Plasmacytoma With Unusual Sunburst Periosteal Reaction.肋骨浆细胞瘤伴不典型日光放射状骨膜反应。
Clin Nucl Med. 2020 Jun;45(6):461-462. doi: 10.1097/RLU.0000000000003030.
2
Solitary Plasmacytoma: a Review of Diagnosis and Management.孤立性浆细胞瘤:诊断与治疗综述
Curr Hematol Malig Rep. 2019 Apr;14(2):63-69. doi: 10.1007/s11899-019-00499-8.
3
Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel.孤立性浆细胞瘤的诊断、治疗和反应评估:欧洲专家小组的最新建议。
J Hematol Oncol. 2018 Jan 16;11(1):10. doi: 10.1186/s13045-017-0549-1.
4
Surgery combined with radiotherapy for the treatment of solitary plasmacytoma of the rib: a case report and review of the literature.
J Cardiothorac Surg. 2015 Oct 13;10:125. doi: 10.1186/s13019-015-0335-5.
5
[Solitary plasmacytoma of the rib: about a case].[肋骨孤立性浆细胞瘤:病例报告]
Pan Afr Med J. 2014 Jun 24;18:179. doi: 10.11604/pamj.2014.18.179.2550. eCollection 2014.
6
Plasmacytoma presenting as missing rib on chest film: a case report and review of the literature.胸部X光片显示肋骨缺失的浆细胞瘤:一例病例报告及文献综述
J La State Med Soc. 2014 Mar-Apr;166(2):63-6. Epub 2014 Apr 10.
7
Surgical resection of a solitary plasmacytoma originating in a rib.起源于肋骨的孤立性浆细胞瘤的手术切除
Ann Thorac Cardiovasc Surg. 2014;20 Suppl:609-12. doi: 10.5761/atcs.cr.12-02235. Epub 2013 Oct 3.
8
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Rib plasmacytoma and IgA multiple myeloma with hyperviscosity syndrome.肋骨浆细胞瘤和伴有高黏滞血症综合征的 IgA 多发性骨髓瘤。
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