1College of Medicine, University of Cincinnati.
2Department of Neurosurgery, University of Cincinnati; and.
Neurosurg Focus. 2022 Sep;53(3):E7. doi: 10.3171/2022.6.FOCUS22253.
The benefit of antibiotic irrigation for prophylaxis against wound infections, not only for traumatic cranial injuries but also in elective neurosurgical care, has recently been called into question. Several articles have cast doubt on the utility of topical antibiotics, and recently, bacitracin irrigation was made unavailable in some US markets. The pervasive nature of antibiotic irrigation, considering the lack of evidence supporting its use, led the authors to question when and how neurosurgeons started using antibiotic irrigation in cranial neurosurgery. Through a review of historical literature, they highlight the adoption of antibiotic irrigation as it began in battlefield surgical practice, gradually leading to the modern concept of antibiotic prophylaxis in civilian and military care.
抗生素冲洗在预防创伤性颅脑损伤和择期神经外科手术中的感染的益处最近受到质疑。有几篇文章对局部使用抗生素的有效性提出了质疑，最近，一些美国市场已经不再使用杆菌肽冲洗。鉴于缺乏支持其使用的证据，抗生素冲洗的广泛应用促使作者质疑神经外科医生何时以及如何开始在颅脑神经外科中使用抗生素冲洗。通过对历史文献的回顾，他们强调了抗生素冲洗的采用，因为它始于战场外科实践，逐渐导致了民用和军用抗生素预防的现代概念。
