Kim Kyung Soo, Min Hyun Jin
Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang UniversityCollege of Medicine, Seoul, Korea.
Ear Nose Throat J. 2025 Mar;104(1_suppl):150S-152S. doi: 10.1177/01455613221125923. Epub 2022 Sep 2.
Fungus ball is a common disease encountered in rhinology departments. As it usually affects immunocompetent patients, other systemic diseases occurring concurrently with fungus ball have not been reported often. Recently, we encountered a patient who was diagnosed with fungus ball in the maxillary sinus and underwent endoscopic sinus surgery. During the surgery, fungus ball-like materials were sucked out and a maxillary sinus mucosal biopsy was performed. The post-operative pathologic report demonstrated that there were many plasma cells; the patient underwent several additional tests in our hematologic department. Finally, he was diagnosed with monoclonal gammopathy of undetermined significance (MGUS). In the present report, we summarize our experience with this patient and share the lessons that we have learned from this case.
真菌球是鼻科常见疾病。由于其通常影响免疫功能正常的患者，因此与真菌球同时发生的其他全身性疾病鲜有报道。最近，我们遇到一名被诊断为上颌窦真菌球并接受了鼻内镜鼻窦手术的患者。手术过程中，吸出了真菌球样物质，并对上颌窦黏膜进行了活检。术后病理报告显示有许多浆细胞；该患者在我们血液科又接受了多项检查。最终，他被诊断为意义未明的单克隆丙种球蛋白病（MGUS）。在本报告中，我们总结了该患者的诊疗经验，并分享了从该病例中学到的经验教训。
