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腹腔镜与开放手术修复先天性十二指肠梗阻:一项系统评价与荟萃分析。

Laparoscopic versus open repair of congenital duodenal obstruction: a systematic review and meta-analysis.

作者信息

Zhang Jie, Xu Xiaoqi, Wang Xiaoman, Zhao Lingling, Lv Yaxin, Chen Kuai

机构信息

Department of Pediatric Surgery, Hangzhou Children's Hospital, Hangzhou, China.

Department of Pediatrics, The Fourth Clinical Medical College of Zhejiang, Chinese Medical University, Hangzhou, China.

出版信息

Pediatr Surg Int. 2022 Nov;38(11):1507-1515. doi: 10.1007/s00383-022-05209-9. Epub 2022 Sep 2.

Abstract

PURPOSE

To assess the safety and efficacy of laparoscopic versus open repair of congenital duodenal obstruction (CDO), we conducted a systematic review and meta-analysis (CDO).

METHODS

A literature search was conducted to identify studies that compared laparoscopic surgery (LS) and open surgery (OS) for neonates with CDO. Meta-analysis was used to pool and compare variables such as operative time, time to feeding, length of hospital stay, anastomotic leak or stricture, postoperative ileus, wound infection, and overall postoperative complications.

RESULTS

Among the 1348 neonatal participants with CDO in the ten studies, 304 received LS and 1044 received OS. When compared to the OS approach, the LS approach resulted in shorter hospital stays, faster time to initial and full feeding, longer operative time, and less wound infection. However, no significant difference in secondary outcomes such as anastomotic leak or stricture, postoperative ileus, and overall postoperative complications was found between LS and OS.

CONCLUSIONS

LS is a safe, feasible and effective surgical procedure for neonatal CDO when compared to OS. Compared with OS, LS has a faster time to feeding, a shorter hospital stay, and less wound infection. Furthermore, in terms of anastomotic leak or stricture, postoperative ileus, and overall postoperative complications, LS is equivalent to OS. We conclude that LS should be considered an acceptable option for CDO.

摘要

目的

为评估腹腔镜手术与开放手术治疗先天性十二指肠梗阻(CDO)的安全性和有效性,我们进行了一项系统评价和荟萃分析(CDO)。

方法

进行文献检索,以确定比较腹腔镜手术(LS)和开放手术(OS)治疗新生儿CDO的研究。荟萃分析用于汇总和比较手术时间、开始喂养时间、住院时间、吻合口漏或狭窄、术后肠梗阻、伤口感染和术后总体并发症等变量。

结果

在十项研究中的1348例患有CDO的新生儿参与者中,304例接受了LS,1044例接受了OS。与OS方法相比,LS方法导致住院时间更短、开始初次和完全喂养的时间更快、手术时间更长以及伤口感染更少。然而,在LS和OS之间,在诸如吻合口漏或狭窄、术后肠梗阻和术后总体并发症等次要结局方面未发现显著差异。

结论

与OS相比,LS是治疗新生儿CDO的一种安全、可行且有效的手术方法。与OS相比,LS开始喂养的时间更快、住院时间更短且伤口感染更少。此外,在吻合口漏或狭窄、术后肠梗阻和术后总体并发症方面,LS与OS相当。我们得出结论,LS应被视为CDO的一种可接受的选择。

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