Vogler Katharina, Daboul Amro, Obst Anne, Fietze Ingo, Ewert Ralf, Biffar Reiner, Krüger Markus
Department of Prosthodontics, Gerodontolgy, and Biomaterials, University Medicine Greifswald, Greifswald, Germany.
Interdisziplinäres Schlafmedizinisches Zentrum, Charité - Universitätsmedizin Berlin, Berlin, Germany.
J Sleep Res. 2023 Feb;32(1):e13702. doi: 10.1111/jsr.13702. Epub 2022 Aug 21.
Obstructive sleep apnea is known to be an overall public health problem that, among other things, increases morbidity and mortality. Risk factors as well as symptoms of this multidimensional sleep-related breathing disorder negatively affect quality of life. With our study we aimed to expose the association between obstructive sleep apnea and quality of life in the population of Pomerania, Germany. We utilized data from the population-based Study of Health in Pomerania (SHIP). Information on health status and risk factors about 4420 participants (2275 women) were gathered within the cohort SHIP-TREND, of which 1209 (559 women) underwent an overnight polysomnography and completed sleep questionnaires. The quality of life of the participants was measured using the Short-Form 12 questionnaire. For our study, an ordinal regression analysis with age, sex, body mass index and the Short-Form 12 health survey as predictors for apnea-hypopnea index was computed. The potential factors affecting quality of life are different between physical and mental dimensions of quality of life. Significant effects were found regarding age, sex, body mass index and the Short-Form 12 Mental Component Score, but not the Physical Component Score.
阻塞性睡眠呼吸暂停是一个公认的公共卫生问题，它会增加发病率和死亡率等。这种多维度的与睡眠相关的呼吸障碍的风险因素和症状会对生活质量产生负面影响。我们的研究旨在揭示德国波美拉尼亚地区人群中阻塞性睡眠呼吸暂停与生活质量之间的关联。我们利用了基于人群的波美拉尼亚健康研究（SHIP）的数据。在SHIP-TREND队列中收集了约4420名参与者（2275名女性）的健康状况和风险因素信息，其中1209名（559名女性）接受了夜间多导睡眠图检查并完成了睡眠问卷。使用简短健康调查问卷12（Short-Form 12 questionnaire）对参与者的生活质量进行了测量。在我们的研究中，计算了以年龄、性别、体重指数和简短健康调查问卷12作为呼吸暂停低通气指数预测因素的有序回归分析。影响生活质量的潜在因素在生活质量的身体维度和心理维度之间有所不同。在年龄、性别、体重指数和简短健康调查问卷12心理成分得分方面发现了显著影响，但在身体成分得分方面未发现显著影响。
