SPARC 与炎症衰老的关联。
A SPARC-ling link to inflammaging.
机构信息
Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Geriatric Research and Education and Clinical Center, Veterans Administration Palo Alto Health Care System, Palo Alto, CA, USA.
出版信息
Sci Immunol. 2022 Sep 2;7(75):eade5698. doi: 10.1126/sciimmunol.ade5698.
PMID:36054338
Abstract
Adipocyte derived SPARC induces pro-inflammatory changes to macrophages, leading to aging that can be reduced by caloric restriction.
摘要
脂肪细胞衍生的 SPARC 诱导巨噬细胞发生促炎变化，导致衰老，而热量限制可减少这种衰老。
Zotero 插件