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阿片类物质使用障碍的药物治疗-更新与当前挑战。

Pharmacotherapy of Opioid Use Disorder-Update and Current Challenges.

机构信息

Department of Medicine, Division of Addiction Medicine, Johns Hopkins School of Medicine, 5200 Eastern Avenue, Mason F. Lord Building, East Tower, 2nd Floor, Baltimore, MD 21224, USA.

Department of Medicine, Division of Addiction Medicine, Johns Hopkins School of Medicine, 5200 Eastern Avenue, Mason F. Lord Building, East Tower, 2nd Floor, Baltimore, MD 21224, USA.

出版信息

Psychiatr Clin North Am. 2022 Sep;45(3):335-346. doi: 10.1016/j.psc.2022.04.001. Epub 2022 Jul 31.

DOI:10.1016/j.psc.2022.04.001
PMID:36055727
Abstract

The incidence of opioid use disorder (OUD) and overdose deaths is rising yearly within the United States. Many cases are associated with illicitly manufactured fentanyl use. In addition to offering patients medications for OUD (methadone, buprenorphine, and naltrexone), the approach to this epidemic should involve increasing provider awareness and education about substance use disorders, expanding urine toxicology screens to test for fentanyl, and using low-threshold treatment approaches.

摘要

在美国,阿片类药物使用障碍(OUD)和过量死亡的发病率每年都在上升。许多病例都与非法制造的芬太尼的使用有关。除了为 OUD 患者提供药物治疗(美沙酮、丁丙诺啡和纳曲酮)外,应对这一流行疾病的方法还应包括提高医务人员对物质使用障碍的认识和教育,扩大尿液毒理学检测以检测芬太尼,并采用低门槛的治疗方法。

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