Makrygiannakis Miltiadis A, Athanasiou Charikleia A, Kaklamanos Eleftherios G
School of Dentistry, National and Kapodistrian University of Athens, Greece.
Department of Dentistry, European University Cyprus, Nicosia, Cyprus.
Eur J Orthod. 2023 Mar 31;45(2):186-195. doi: 10.1093/ejo/cjac052.
Humans may consume various beverages in everyday life. Previous research has shown that the administration of different substances (medicinal or not) may affect bone turnover and, thus, orthodontic tooth movement. It would be anticipated that the substances contained in beverages could have an impact on tooth movement, as well.
To investigate in a systematic way and appraise the quality of the available evidence from animal studies regarding the impact of various drinks or the main ingredients included in beverages on the rate of orthodontic tooth movement.
Search without restriction in six databases (including grey literature) and hand searching were performed until March 2022.
We looked for controlled animal studies investigating the effect of drinks, or the main ingredients included in beverages, on the rate of orthodontic tooth movement.
After study retrieval and selection, relevant data was extracted, and the risk of bias was assessed using the SYRCLE's Risk of Bias Tool. The quality of available evidence was assessed with the Grades of Recommendation, Assessment, Development, and Evaluation.
The initially identified records were finally reduced to nine studies conducted on animals. Carbonated soft drinks were shown to decrease the rate of tooth movement, but alcohol consumption did not have an impact. Exploratory meta-analysis showed that caffeine exhibited an acceleratory effect after 3 weeks of force application. Exploratory meta-regression results indicated that high dosages of caffeine reduced the rate of tooth movement.
The located animal experiments reported that caffeine accelerates, carbonated drinks decelerate, while alcohol does not affect the rate of orthodontic tooth movement. However, due to various limitations it remains unclear whether caffeine, alcohol, or carbonated drinks finally influence tooth movement in animal studies.
Open Science Framework (https://osf.io/jyhbd/).
人类在日常生活中可能会饮用各种饮料。先前的研究表明，摄入不同物质（无论是否为药物）可能会影响骨转换，进而影响正畸牙齿移动。可以预期，饮料中所含的物质也可能对牙齿移动产生影响。
系统地调查并评估动物研究中有关各种饮料或饮料中的主要成分对正畸牙齿移动速率影响的现有证据的质量。
在六个数据库（包括灰色文献）中进行无限制检索，并进行手工检索，直至2022年3月。
我们寻找对照动物研究，以调查饮料或饮料中的主要成分对正畸牙齿移动速率的影响。
在检索和筛选研究后，提取相关数据，并使用SYRCLE偏倚风险工具评估偏倚风险。使用推荐分级、评估、制定和评价（GRADE）方法评估现有证据的质量。
最初识别的记录最终缩减为九项针对动物的研究。碳酸软饮料被证明会降低牙齿移动速率，但饮酒没有影响。探索性荟萃分析表明，在施加力3周后，咖啡因表现出加速作用。探索性元回归结果表明，高剂量咖啡因会降低牙齿移动速率。
所找到的动物实验报告称，咖啡因会加速正畸牙齿移动，碳酸饮料会使其减速，而酒精不会影响正畸牙齿移动速率。然而，由于各种局限性，在动物研究中，咖啡因、酒精或碳酸饮料最终是否会影响牙齿移动仍不清楚。
开放科学框架（https://osf.io/jyhbd/）
