Department of Psychiatry, Ajou University School of Medicine, Suwon, Republic of Korea; Suwon Geriatric Mental Health Center, Suwon, Republic of Korea.
Department of Psychology, University of California, Berkeley, California, United States of America.
J Affect Disord. 2022 Dec 1;318:185-190. doi: 10.1016/j.jad.2022.08.117. Epub 2022 Aug 31.
The moderating effect of cognitive function on the association between social support and late-life depressive symptoms has not been thoroughly investigated. Identifying cognitive function as a possible moderator of this association might help plan community-based interventions for late-life depressive symptoms.
Participants were community-dwelling older adults who visited a community-based mental health center. The ENRICHD Social Support Instrument and the Montgomery-Asberg Depression Rating Scale were used to evaluate social support and depressive symptoms, respectively. Cognitive function was assessed using the Korean version of the Mini-Mental State Examination. Data from 1088 and 506 participants were included in the cross-sectional and longitudinal analyses, respectively. Multiple linear regression analysis was performed to assess the effects of social support on depressive symptoms and the possible moderating effect of cognition.
After adjusting for possible confounders, greater social support at baseline was associated with fewer depressive symptoms in both cross-sectional (estimate = -0.25 standard error [SE] = 0.03, P < 0.001) and longitudinal analyses (estimate = -0.11, SE = 0.05, P = 0.014). Moreover, the association between social support and depressive symptoms was significantly moderated by cognitive function (P for interaction < 0.001 for cross-sectional analysis, and P for interaction = 0.011 for longitudinal analysis).
The tool for assessing social support was self-reported. There may have been a selection bias in the study sample.
Greater social support was associated with fewer late-life depressive symptoms in both analyses. However, social support may have less benefits for alleviating depressive symptoms in older adults with cognitive decline.
认知功能对社会支持与老年期抑郁症状之间关联的调节作用尚未得到充分研究。确定认知功能是否为这种关联的一个可能的调节因素,可能有助于为老年期抑郁症状制定基于社区的干预措施。
参与者为到社区心理健康中心就诊的社区居住的老年人。使用 ENRICHD 社会支持量表和蒙哥马利-阿斯伯格抑郁评定量表分别评估社会支持和抑郁症状。使用韩国版简易精神状态检查评估认知功能。分别纳入了 1088 名和 506 名参与者进行横断面和纵向分析。采用多元线性回归分析评估社会支持对抑郁症状的影响,以及认知的可能调节作用。
在调整了可能的混杂因素后,基线时的社会支持程度越高,在横断面分析(估计值为 -0.25,标准误为 0.03,P<0.001)和纵向分析(估计值为 -0.11,标准误为 0.05,P=0.014)中,抑郁症状越少。此外,社会支持与抑郁症状之间的关联受到认知功能的显著调节(横断面分析的交互作用 P<0.001,纵向分析的交互作用 P=0.011)。
评估社会支持的工具是自我报告的。研究样本可能存在选择偏倚。
在这两种分析中,更多的社会支持与更少的老年期抑郁症状相关。然而,对于认知能力下降的老年人来说,社会支持可能对减轻抑郁症状的益处较小。