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经漫射光学测量验证的微型化天线,用于区分天然和煮沸的脂肪组织。

Miniaturized antenna verified with diffuse optical measurements for native and boiled adipose tissue differentiation.

机构信息

Department of Communication, Faculty of Engineering, Canadian International College (CIC), Cairo, Egypt.

Department of Engineering Applications of Lasers, National Institute of Laser Enhanced Sciences, Cairo University, Giza, Egypt.

出版信息

Sci Rep. 2022 Sep 3;12(1):15035. doi: 10.1038/s41598-022-19430-y.

Abstract

Medical industries are continuously working towards the development of wearable theragnostic devices which enable monitoring various ailments in the body and then transmitting them to the base-station. The antenna design is of prime importance where the suitable design guarantees proper communication between the antenna and the base-station. In this paper, a co-planar wave-guide antenna is proposed for the use in the medical implant communication service (MICS) band for data transmission. The proposed antenna is studied for ex-vivo applications where the antenna is simulated for bovine intramuscular fat (adipose tissue). The preliminary results showed that the antenna radiates in MICS band. Two types of samples are tested; namely, native fat and boiled fat. The boiled fat is used in order to represent the infected fat tissue. Hence, the antenna was implanted into the fat samples and the results revealed noticeable variations in the radiation characteristics between native and boiled fat. Different parameters of the proposed antenna including the reflection coefficient (S), radiation patterns, gain, efficiency, and front-to-back ratio are investigated. The simulations showed that S parameter was - 12.4 dB in MICS band for the normal fat. On the other hand, the measured S values were - 12.3 dB for the native samples and - 9.9 dB for the boiled fat samples. To assert the variation in the biological characteristics of the boiled fat as compared to those of the native fat, diffuse optical measurements of the examined samples were investigated. Such variation in the light scattering and absorbance by the tissue is responsible for varying the S parameter for each case. The results have shown that the proposed design is a good candidate for detecting the change in biological tissue.

摘要

医疗行业一直在努力开发可穿戴治疗诊断设备,这些设备能够监测体内的各种疾病,然后将其传输到基站。天线设计至关重要,合适的设计可确保天线与基站之间的良好通信。本文提出了一种共面波导天线,用于医疗植入通信服务(MICS)频段的数据传输。该天线用于牛肌肉内脂肪(脂肪组织)的离体应用进行了研究。初步结果表明,该天线在 MICS 频段辐射。测试了两种类型的样品,即天然脂肪和煮沸脂肪。煮沸的脂肪用于表示感染的脂肪组织。因此,将天线植入脂肪样本中,结果显示天然脂肪和煮沸脂肪之间的辐射特性有明显变化。研究了所提出天线的不同参数,包括反射系数(S)、辐射模式、增益、效率和前后比。模拟结果表明,正常脂肪的 MICS 频段的 S 参数为−12.4dB。另一方面,天然样品的实测 S 值为−12.3dB,煮沸脂肪样品的实测 S 值为−9.9dB。为了证明煮沸脂肪的生物学特性与天然脂肪的差异,对检查样品进行了漫射光学测量。组织的光散射和吸收率的这种变化导致每个案例的 S 参数变化。结果表明,所提出的设计是检测生物组织变化的良好候选方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/827a/9440913/5e9a934df8ae/41598_2022_19430_Fig1_HTML.jpg

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