比利时猪品种中的血清蛋白酶抑制剂连锁群。

The serum protease inhibitor linkage group in Belgian pig breeds.

作者信息

van de Weghe A, van Zeveren A, Bouquet Y, Varewyck H

出版信息

Anim Genet. 1987;18(1):63-9. doi: 10.1111/j.1365-2052.1987.tb00744.x.

DOI:10.1111/j.1365-2052.1987.tb00744.x

Abstract

Genetic variants of pig serum alpha-protease inhibitors (protease inhibitors-1 and -2, PI1 and PI2; postalbumin-1A and -1B, PO1A and PO1B) were studied by 2-D electrophoresis of serum samples. The inheritance data confirmed the close linkage between the loci of these inhibitors. The order between these loci was indicated as Pi1-Po1A-Po1B-Pi2 and these were spread over a distance of about 1 cM. Very strong linkage disequilibrium was observed between the alleles at these loci. The two breeds studied (Belgian Landrace and Piétrain) showed very different allele and haplotype frequencies. Both breeds showed extensive polymorphism at Po1A and Pi2 loci.

摘要

通过血清样本的二维电泳研究了猪血清α-蛋白酶抑制剂（蛋白酶抑制剂-1和-2，PI1和PI2；后白蛋白-1A和-1B，PO1A和PO1B）的遗传变异。遗传数据证实了这些抑制剂基因座之间的紧密连锁。这些基因座之间的顺序为Pi1-Po1A-Po1B-Pi2，它们分布在约1厘摩的距离上。在这些基因座的等位基因之间观察到非常强的连锁不平衡。所研究的两个品种（比利时长白猪和皮特兰猪）显示出非常不同的等位基因和单倍型频率。两个品种在Po1A和Pi2基因座上都表现出广泛的多态性。