Spine Center, Department of Orthopaedics, Shanghai Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Huangpu District, Shanghai, China.
Spine Center, Department of Orthopaedics, Shanghai Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Huangpu District, Shanghai, China.
Clin Neurol Neurosurg. 2022 Nov;222:107416. doi: 10.1016/j.clineuro.2022.107416. Epub 2022 Aug 19.
To analyze the significance of ossification index of cervical posterior longitudinal ligament as a risk factor for thoracic OPLL (ossification of the posterior longitudinal ligament) in patients with cervical OPLL.
We retrospectively analyzed the clinical data of cervical OPLL patients in Changzheng hospital, who received chest CT scans for screening of COVID-19, and included 87 patients into this study. According to the radiographic evidence, 87 patients were divided into CT group(cervical OPLL combined with thoracic OPLL）and C group(cervical OPLL group). We measured the cervical OS index (ossification index), and analyzed the relationship between thoracic OPLL and cervical OS index.
There was no difference of age、sex、duration of symptoms、comorbidity between the 2 groups(P＞0.05). The mean cervical OS index was higher in the CT group than in the C group (8 ± 2 VS 3 ± 2，P＜0.001).
Patients with cervical OS index ＞8 was considered as "high risk" of tandem OPLL, while with value ≤ 4 was considered as "low risk". Index between 5 and 8 were considered as "middle risk". This study demonstrated that the cervical OS index may be used as an indicator of thoracic OPLL in patients with cervical OPLL, with a high diagnostic accuracy.
分析颈椎后纵韧带骨化指数（ossification index of cervical posterior longitudinal ligament，C4PI）作为颈椎后纵韧带骨化（ossification of the posterior longitudinal ligament，OPLL）合并胸椎间盘突出症（ossification of the posterior longitudinal ligament，thoracic OPLL）患者发生胸椎间盘突出症的危险因素的意义。
回顾性分析长征医院颈椎 OPLL 患者的临床资料，所有患者均因筛查 COVID-19 而行胸部 CT 扫描，共纳入 87 例患者。根据影像学证据，87 例患者分为 CT 组（颈椎 OPLL 合并胸椎间盘突出症）和 C 组（颈椎 OPLL 组）。测量颈椎后纵韧带骨化指数（ossification index），分析胸椎间盘突出症与颈椎后纵韧带骨化指数的关系。
两组患者在年龄、性别、症状持续时间、并存疾病等方面无差异（P＞0.05）。CT 组的颈椎后纵韧带骨化指数（ossification index）高于 C 组（8±2 比 3±2，P＜0.001）。
颈椎后纵韧带骨化指数＞8 时，考虑为“高位”型颈椎 OPLL 合并胸椎间盘突出症，指数值≤4 时考虑为“低位”型，指数值在 5 到 8 之间时考虑为“中位”型。本研究表明，颈椎后纵韧带骨化指数（ossification index）可能是颈椎 OPLL 患者发生胸椎间盘突出症的一个指标，具有较高的诊断准确性。
