Department of Internal Medicine, The University of Texas Medical Branch at Galveston, Galveston, TX.
Department of Anesthesiology and Perioperative Medicine, Tufts University School of Medicine, Boston, MA.
Mayo Clin Proc. 2022 Sep;97(9):1734-1751. doi: 10.1016/j.mayocp.2022.03.039.
Cardiovascular conditions such as hypertension, arrhythmias, and heart failure are common in patients undergoing anesthesia for surgical or other procedures. Numerous guidelines from various specialty societies offer variable recommendations for the perioperative management of these medications. The Society for Perioperative Assessment and Quality Improvement identified a need to provide multidisciplinary evidence-based recommendations for preoperative medication management. The society convened a group of 13 members with expertise in perioperative medicine and training in anesthesiology or internal medicine. The aim of this consensus effort is to provide perioperative clinicians with guidance on the management of cardiovascular medications commonly encountered during the preoperative evaluation. We used a modified Delphi process to establish consensus. Twenty-one classes of medications were identified: α-adrenergic receptor antagonists, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, angiotensin receptor-neprilysin inhibitors, β-adrenoceptor blockers, calcium-channel blockers, centrally acting sympatholytic medications, direct-acting vasodilators, loop diuretics, thiazide diuretics, potassium-sparing diuretics, endothelin receptor antagonists, cardiac glycosides, nitrodilators, phosphodiesterase-5 inhibitors, class III antiarrhythmic agents, potassium-channel openers, renin inhibitors, class I antiarrhythmic agents, sodium-channel blockers, and sodium glucose cotransportor-2 inhibitors. We provide recommendations for the management of these medications preoperatively.
心血管疾病,如高血压、心律失常和心力衰竭,在接受手术或其他程序麻醉的患者中很常见。许多专业学会的指南都对这些药物的围手术期管理提供了不同的建议。围手术期评估和质量改进协会确定需要为术前药物管理提供多学科循证建议。该协会召集了 13 名成员,他们在围手术期医学方面具有专业知识,并接受过麻醉或内科培训。这项共识工作的目的是为围手术期临床医生提供管理常见于术前评估期间的心血管药物的指导。我们使用改良的 Delphi 过程来建立共识。确定了 21 类药物:α-肾上腺素能受体拮抗剂、血管紧张素转换酶抑制剂、血管紧张素 II 受体阻滞剂、血管紧张素受体-脑啡肽酶抑制剂、β-肾上腺素受体阻滞剂、钙通道阻滞剂、中枢作用的交感神经抑制剂、直接作用的血管扩张剂、袢利尿剂、噻嗪类利尿剂、保钾利尿剂、内皮素受体拮抗剂、强心苷、硝酸酯类、磷酸二酯酶-5 抑制剂、III 类抗心律失常药、钾通道开放剂、肾素抑制剂、I 类抗心律失常药、钠通道阻滞剂和钠葡萄糖共转运蛋白-2 抑制剂。我们提供了这些药物术前管理的建议。