Ceska Slov Farm. 2022 Summer;71(3):91-97.
Metronomic therapy is a therapeutic method in selected oncological diseases, using long-term administration of low doses of drugs with direct or indirect antitumor effect. In addition, to direct cytotoxic eradication of tumor cells, metronomic therapy can very strongly affect the tumor microenvironment; it also has an immunomodulatory and antiangiogenic effect. Its minimal toxic profile allows for use in patients with severe organ dysfunctions and directly impacts the quality of life and social inclusion of oncological patients.
节拍化疗是一种在选定的肿瘤疾病中使用的治疗方法，采用长期给予具有直接或间接抗肿瘤作用的低剂量药物。此外，节拍化疗除了直接细胞毒性消除肿瘤细胞外，还可以非常强烈地影响肿瘤微环境；它还具有免疫调节和抗血管生成作用。其最小的毒性特征使其可用于严重器官功能障碍的患者，并直接影响肿瘤患者的生活质量和社会包容度。
