Center for Marine Environmental Studies, Ehime University.
Graduate School of Science and Engineering, Ehime University.
Microbes Environ. 2022;37(3). doi: 10.1264/jsme2.ME22038.
Integrative and conjugative elements (ICEs) play a role in the horizontal transfer of antibiotic resistance genes (ARGs). We herein report an ICE from Shewanella halifaxensis isolated from fish intestine with a similar structure to both a clinical bacterial ICE and marine bacterial plasmid. The ICE was designated ICEShaJpn1, a member of the SXT/R391 family of ICEs (SRIs). ICEShaJpn1 has a common core structure with SRIs of clinical and fish origins and an ARG cassette with the pAQU1 plasmid of Photobacterium damselae subsp. damselae, suggesting that the common core of SRIs is widely distributed and ARG cassettes are collected from regional bacteria.
整合子-接合元件（ICEs）在抗生素耐药基因（ARGs）的水平转移中发挥作用。我们在此报告了一种来自鱼类肠道的希瓦氏菌属 Shewanella halifaxensis 的 ICE，其结构与临床细菌 ICE 和海洋细菌质粒相似。该 ICE 被命名为 ICEShaJpn1，是 SXT/R391 家族 ICEs（SRIs）的成员。ICEShaJpn1 具有与临床和鱼类来源的 SRI 相同的核心结构，以及来自 Photobacterium damselae subsp. damselae 的 pAQU1 质粒的 ARG 盒，表明 SRI 的共同核心广泛分布，ARG 盒从区域细菌中收集。
