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胃十二指肠神经内分泌肿瘤包括胃泌素瘤——诊断和治疗指南更新(波兰神经内分泌肿瘤网络推荐)

Gastroduodenal neuroendocrine neoplasms including gastrinoma - update of the diagnostic and therapeutic guidelines (recommended by the Polish Network of Neuroendocrine Tumours) [Nowotwory neuroendokrynne żołądka i dwunastnicy z uwzględnieniem gastrinoma - uaktualnione zasady postępowania (rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)].

机构信息

Department of Internal Medicine and Gastroenterology, Central Clinical Hospital of the Ministry of Interior and Administration, Warsaw, Poland.

Department of Endocrinology and Neuroendocrine Tumours, Department of Pathophysiology and Endocrinology, Medical University of Silesia, Katowice, Poland.

出版信息

Endokrynol Pol. 2022;73(3):455-490. doi: 10.5603/EP.a2022.0051.

Abstract

After another meeting of experts of the Polish Network of Neuroendocrine Tumours, updated recommendations for the management of patients with gastric and duodenal neuroendocrine neoplasms, including gastrinoma, have been issued. As before, the epidemiology, pathogenesis and clinical symptoms of these neoplasms have been discussed, as well as the principles of diagnostic procedures, including biochemical and histopathological diagnostics and tumour localisation, highlighting the changes introduced in the recommendations. Updated principles of therapeutic management have also been presented, including endoscopic and surgical treatment, and the options of pharmacological and radioisotope treatment. The importance of monitoring patients with gastric and duodenal NENs, including gastrinoma, has also been emphasised.

摘要

在波兰神经内分泌肿瘤网络专家的另一次会议之后,发布了更新的胃和十二指肠神经内分泌肿瘤(包括胃泌素瘤)患者管理建议。与以往一样,讨论了这些肿瘤的流行病学、发病机制和临床症状,以及诊断程序的原则,包括生化和组织病理学诊断和肿瘤定位,并强调了建议中的变化。还介绍了更新的治疗管理原则,包括内镜和手术治疗,以及药物和放射性同位素治疗的选择。强调了监测胃和十二指肠 NEN 患者(包括胃泌素瘤)的重要性。

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