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严重躁动作为儿童多系统炎症综合征的一种不寻常表现

Severe Agitation as an Unusual Presentation of Multisystem Inflammatory Syndrome in Children.

作者信息

Ghamry Mohamed A, Salib Korlos, Henin Shereen, Salah Rehab, Dobs Monica

机构信息

Pediatrics, Al Salam Hospital, Ministry of Health, Port Said, EGY.

General Practice, El-Demerdash Hospital, Cairo, EGY.

出版信息

Cureus. 2022 Aug 2;14(8):e27621. doi: 10.7759/cureus.27621. eCollection 2022 Aug.

DOI:10.7759/cureus.27621
PMID:36059320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9436482/
Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a rare hyperinflammatory syndrome that mainly affects children after a primary infection with coronavirus disease 2019 (COVID-19), with the possibility of severe and lethal complications. We report a case of a unique presentation of MIS-C in a four-year-old boy who presented with severe agitation, muscle spasms, and two days of fever. Other findings consistent with MIS-C were revealed later, and he was managed with intravenous immunoglobulin (IVIG) and steroids. He showed a dramatic response of improvement and was discharged. This case report aimed to raise health professionals' awareness about the atypical presentations of MIS-C and the importance of early diagnosis, treatment, and follow-up MIS-C cases to avoid complications affecting children's lives.

摘要

儿童多系统炎症综合征(MIS-C)是一种罕见的高炎症综合征,主要影响初次感染2019冠状病毒病(COVID-19)后的儿童,有可能出现严重和致命的并发症。我们报告一例4岁男孩出现的MIS-C独特表现,该男孩表现为严重烦躁、肌肉痉挛和持续两天的发热。后来发现了其他与MIS-C相符的表现,他接受了静脉注射免疫球蛋白(IVIG)和类固醇治疗。他表现出显著的改善反应并出院。本病例报告旨在提高卫生专业人员对MIS-C非典型表现的认识,以及早期诊断、治疗和随访MIS-C病例以避免影响儿童生命的并发症的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/9436482/c654e6a4ac13/cureus-0014-00000027621-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/9436482/c654e6a4ac13/cureus-0014-00000027621-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be1d/9436482/c654e6a4ac13/cureus-0014-00000027621-i01.jpg

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本文引用的文献

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A Case of Multisystem Inflammatory Syndrome in a Three-Year-Old Boy.一名三岁男孩的多系统炎症综合征病例。
Cureus. 2022 Jun 25;14(6):e26315. doi: 10.7759/cureus.26315. eCollection 2022 Jun.
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Multisystem inflammatory syndrome in children (MIS-C): a mini-review.儿童多系统炎症综合征(MIS-C):一篇综述短文
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Neuropsychiatric Symptoms in an Adolescent Boy With Multisystem Inflammatory Syndrome in Children.一名患有儿童多系统炎症综合征的青少年男孩的神经精神症状
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JAMA. 2020 Jul 21;324(3):259-269. doi: 10.1001/jama.2020.10369.
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Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study.法国巴黎新冠疫情期间儿童川崎样多系统炎症综合征:前瞻性观察研究。
BMJ. 2020 Jun 3;369:m2094. doi: 10.1136/bmj.m2094.
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Septic shock presentation in adolescents with COVID-19.新冠病毒感染青少年患者的感染性休克表现
Lancet Child Adolesc Health. 2020 Jul;4(7):e21-e23. doi: 10.1016/S2352-4642(20)30164-4. Epub 2020 May 20.
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