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腹腔镜下转移性结肠癌射频消融术后肝脓肿形成

Liver Abscess Formation After Laparoscopic Radiofrequency Ablation of Metastatic Colon Cancer.

作者信息

Cecchini Arthur, Othman Ahmad, Burgess Ryan, Sadiq Madeeha S, Cecchini Amanda

机构信息

Internal Medicine, East Tennessee State University Quillen College of Medicine, Johnson City, USA.

Pulmonary and Critical Care Medicine, Eastern Virginia Medical School, Norfolk, USA.

出版信息

Cureus. 2022 Aug 1;14(8):e27556. doi: 10.7759/cureus.27556. eCollection 2022 Aug.

DOI:10.7759/cureus.27556
PMID:36059345
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9429521/
Abstract

Radiofrequency ablation (RFA) may be used to treat either benign or malignant tumors of the liver. Complications are relatively rare, with the most common being pyogenic liver abscess formation. Risk factors for pyogenic liver abscess formation include Child-Pugh class B or C cirrhosis, biliary tract disease, diabetes mellitus, and preexisting biliary diversion. Differentiating sterile post-ablative necrosis from abscess formation may be difficult on imaging as air may be considered a normal post-ablation finding. Treatment of pyogenic liver abscesses includes drainage and antibiotics targeting the most common organisms. This case presents a 71-year-old female with none of the above risk factors who developed a pyogenic liver abscess after undergoing RFA for a solitary liver metastasis secondary to biopsy-proven colonic adenocarcinoma. She was successfully treated with antibiotics and an indwelling percutaneous drain.

摘要

射频消融(RFA)可用于治疗肝脏的良性或恶性肿瘤。并发症相对少见,最常见的是化脓性肝脓肿形成。化脓性肝脓肿形成的危险因素包括Child-Pugh B级或C级肝硬化、胆道疾病、糖尿病以及既往存在的胆道改道。在影像学上区分无菌性消融后坏死与脓肿形成可能较为困难,因为空气可能被视为消融后的正常表现。化脓性肝脓肿的治疗包括引流以及针对最常见病原体的抗生素治疗。该病例为一名71岁女性,无上述任何危险因素,在因经活检证实的结肠腺癌继发的孤立性肝转移接受RFA治疗后发生了化脓性肝脓肿。她通过抗生素和留置经皮引流管成功治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fac8/9429521/b878268b7ddd/cureus-0014-00000027556-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fac8/9429521/2faab0977d4e/cureus-0014-00000027556-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fac8/9429521/8d8f42e43982/cureus-0014-00000027556-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fac8/9429521/f99044ffad1d/cureus-0014-00000027556-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fac8/9429521/76dafd0d8123/cureus-0014-00000027556-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fac8/9429521/16105d5d596b/cureus-0014-00000027556-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fac8/9429521/b878268b7ddd/cureus-0014-00000027556-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fac8/9429521/2faab0977d4e/cureus-0014-00000027556-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fac8/9429521/8d8f42e43982/cureus-0014-00000027556-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fac8/9429521/f99044ffad1d/cureus-0014-00000027556-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fac8/9429521/76dafd0d8123/cureus-0014-00000027556-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fac8/9429521/16105d5d596b/cureus-0014-00000027556-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fac8/9429521/b878268b7ddd/cureus-0014-00000027556-i06.jpg

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本文引用的文献

1
Pyogenic liver abscess.化脓性肝脓肿
Clin Liver Dis (Hoboken). 2015 Aug 24;6(2):51-54. doi: 10.1002/cld.487. eCollection 2015 Aug.
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Characteristics and management of pyogenic liver abscess: A European experience.化脓性肝脓肿的特征与管理:欧洲经验
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Radiofrequency ablation of hepatocellular carcinoma as bridge therapy to liver transplantation: A 10-year intention-to-treat analysis.射频消融治疗肝细胞癌作为肝移植桥接治疗:10 年意向治疗分析。
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Incidence and Risk Factors for Liver Abscess After Thermal Ablation of Liver Neoplasm.肝脏肿瘤热消融术后肝脓肿的发生率及危险因素
Hepat Mon. 2016 May 23;16(7):e34588. doi: 10.5812/hepatmon.34588. eCollection 2016 Jul.
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Percutaneous needle aspiration versus catheter drainage in the management of liver abscess: a systematic review and meta-analysis.经皮针吸术与导管引流术治疗肝脓肿的系统评价和荟萃分析
HPB (Oxford). 2015 Mar;17(3):195-201. doi: 10.1111/hpb.12332. Epub 2014 Sep 10.
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Tumor ablation: common modalities and general practices.肿瘤消融:常见方式与一般实践
Tech Vasc Interv Radiol. 2013 Dec;16(4):192-200. doi: 10.1053/j.tvir.2013.08.002.
7
Frequency of and risk factors for complications after liver radiofrequency ablation under CT fluoroscopic guidance in 1500 sessions: single-center experience.在 CT 透视引导下进行 1500 次肝射频消融术的并发症发生频率和危险因素:单中心经验。
AJR Am J Roentgenol. 2013 Mar;200(3):658-64. doi: 10.2214/AJR.12.8691.
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EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma.欧洲肝脏研究学会-欧洲肿瘤内科学会临床实践指南:肝细胞癌的管理
J Hepatol. 2012 Apr;56(4):908-43. doi: 10.1016/j.jhep.2011.12.001.
9
Liver abscess after radiofrequency ablation of tumors in patients with a biliary tract procedure.接受过胆道手术的患者在肿瘤射频消融术后发生肝脓肿。
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10
Liver abscess after percutaneous radiofrequency ablation for hepatocellular carcinomas: frequency and risk factors.肝细胞癌经皮射频消融术后肝脓肿:发生率及危险因素
AJR Am J Roentgenol. 2005 Jun;184(6):1860-7. doi: 10.2214/ajr.184.6.01841860.