Zimmerman M C, Morgan D E, Dubno J R
Ann Otol Rhinol Laryngol. 1987 May-Jun;96(3 Pt 1):291-9. doi: 10.1177/000348948709600311.
The auditory brain stem response (ABR) of a single group of developing normal infants was examined longitudinally, from newborn through 6 months of age. A sufficiently broad range of stimulus variables was included to ensure that the auditory system was adequately sampled in order to demonstrate developmental principles. Findings indicate that there are no differences in wave V latency-intensity functions between infants and adults. For waves I, III, and V, absolute and interwave latency-repetition rate functions differ between infants and adults and undergo systematic changes throughout the first 6 months of life. The most dramatic ABR changes (between any two sequential test sessions in infants) occurred between the ages of newborn and 2 weeks, with less pronounced ABR changes beyond 2 weeks of age. The pattern of latency change for wave I was different from that for waves III and V. After 2 weeks of age, wave I latency was the same as the adult value at all repetition rates. In contrast, waves III and V were characterized by decreasing latency throughout the follow-up period. A curvilinear developmental model provided a satisfactory fit to ABR latency data.
对一组发育正常的婴儿从出生到6个月大进行了纵向听觉脑干反应（ABR）检测。纳入了足够广泛的刺激变量，以确保对听觉系统进行充分采样，从而证明发育规律。研究结果表明，婴儿和成人之间V波潜伏期-强度函数没有差异。对于I波、III波和V波，婴儿和成人之间的绝对潜伏期和波间潜伏期-重复率函数不同，并且在生命的前6个月会发生系统性变化。婴儿期（任意两个连续测试阶段之间）最显著的ABR变化发生在出生至2周龄之间，2周龄之后ABR变化不太明显。I波的潜伏期变化模式与III波和V波不同。2周龄后，I波潜伏期在所有重复率下都与成人值相同。相比之下，III波和V波的特点是在整个随访期间潜伏期逐渐缩短。一个曲线发育模型能够很好地拟合ABR潜伏期数据。
