Crook Matt, Carvajal Tanya, Davis Payton, Ferdush Jannatul, Page Robert B, Tennyson Elaine
Texas A&M University-San Antonio.
MicroPubl Biol. 2022 Aug 17;2022. doi: 10.17912/micropub.biology.000629. eCollection 2022.
Development is a process that occurs over time, but defects are often scored at the end point of the process being studied. We are interested in understanding the molecular basis of gonad development in and have used the Distal Tip Cell marker to develop a larval size model of gonad growth. We found that gonad length demonstrates two distinct phases relative to larval length, with a breakpoint in mid-L3 stage. We hope that this model will help determine at what point in gonad development our genes of interest act.
发育是一个随时间发生的过程，但缺陷通常在所研究过程的终点进行评分。我们有兴趣了解[未提及具体物种名称]性腺发育的分子基础，并使用远端顶端细胞标记物建立了性腺生长的幼虫大小模型。我们发现，相对于幼虫长度，性腺长度表现出两个不同的阶段，在L3中期有一个断点。我们希望这个模型将有助于确定我们感兴趣的基因在性腺发育的哪个阶段起作用。
