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复发性恶性血管间叶肿瘤(横纹肌肉瘤)的罕见病例。

A Rare Occurrence of Relapse Malignant Vascular Mesenchymal Tumors (Rhabdomyosarcoma).

作者信息

Munjewar Pratiksha K, Sharma Dr Ranjana, Wanjari Mayur B, Kantode Vaishnavi V

机构信息

Medical Surgical Nursing, Srimati Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Medical Sciences, Wardha, IND.

Community Health Nursing, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, IND.

出版信息

Cureus. 2022 Jul 31;14(7):e27525. doi: 10.7759/cureus.27525. eCollection 2022 Jul.

DOI:10.7759/cureus.27525
PMID:36060346
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9427127/
Abstract

Relapsed rhabdomyosarcoma (RMS) has several therapeutic challenges. The novel treatment for relapsed RMS was surgical management, chemotherapy, and radiotherapy. Reoccurrence significantly occurs in children and adolescents. RMS occurs anywhere in the body but mostly occurs in the legs, head, neck, urinary, and reproductive systems. Here, we present the case of a 19-year-old female who came to the emergency department with complaints of swelling in the left side of the neck that extended toward the face and left eye, breathlessness, and vomiting for one month. She has a history of peripheral nerve sheath tumor and type 1 diabetes mellitus. Surgical management was done through excision of the mesenchymal tumor surgery, and the patient's prognosis was good.

摘要

复发性横纹肌肉瘤(RMS)存在若干治疗挑战。复发性RMS的新型治疗方法为手术治疗、化疗和放疗。复发在儿童和青少年中显著发生。RMS可发生于身体的任何部位,但最常见于腿部、头部、颈部、泌尿系统和生殖系统。在此,我们报告一例19岁女性病例,该患者因左侧颈部肿胀并蔓延至面部和左眼、呼吸急促及呕吐1个月前来急诊科就诊。她有周围神经鞘瘤病史和1型糖尿病史。通过间叶性肿瘤切除术进行了手术治疗,患者预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18f2/9427127/1c5c12b77b70/cureus-0014-00000027525-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18f2/9427127/1c5c12b77b70/cureus-0014-00000027525-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18f2/9427127/1c5c12b77b70/cureus-0014-00000027525-i01.jpg

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本文引用的文献

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Recent Advances and Challenges in the Treatment of Rhabdomyosarcoma.横纹肌肉瘤治疗的最新进展与挑战
Cancers (Basel). 2020 Jul 2;12(7):1758. doi: 10.3390/cancers12071758.
2
Current and Future Treatment Strategies for Rhabdomyosarcoma.横纹肌肉瘤的当前及未来治疗策略
Front Oncol. 2019 Dec 20;9:1458. doi: 10.3389/fonc.2019.01458. eCollection 2019.
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Refinement of risk stratification for childhood rhabdomyosarcoma using FOXO1 fusion status in addition to established clinical outcome predictors: A report from the Children's Oncology Group.
除了既定的临床预后预测因素外,利用 FOXO1 融合状态对儿童横纹肌肉瘤进行风险分层的精细化:来自儿童肿瘤学组的报告。
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Rhabdomyosarcoma.横纹肌肉瘤。
Nat Rev Dis Primers. 2019 Jan 7;5(1):1. doi: 10.1038/s41572-018-0051-2.
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Sarcomas.肉瘤
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Does surgery have a role in the treatment of local relapses of non-metastatic rhabdomyosarcoma?手术在治疗非转移性横纹肌肉瘤的局部复发病灶中是否具有作用?
Pediatr Blood Cancer. 2011 Dec 15;57(7):1261-5. doi: 10.1002/pbc.23225. Epub 2011 Aug 8.
7
Initial patient characteristics can predict pattern and risk of relapse in localized rhabdomyosarcoma.初始患者特征可预测局限性横纹肌肉瘤的复发模式和风险。
J Clin Oncol. 2008 Jan 20;26(3):406-13. doi: 10.1200/JCO.2007.12.2382.
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J Pediatr Surg. 2006 Apr;41(4):633-8; discussion 633-8. doi: 10.1016/j.jpedsurg.2005.12.002.
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Outcomes and prognostic factors after recurrence in children and adolescents with nonmetastatic rhabdomyosarcoma.非转移性横纹肌肉瘤儿童和青少年复发后的结局及预后因素
Cancer. 2005 Jul 1;104(1):183-90. doi: 10.1002/cncr.21138.
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Intraosseous rhabdomyosarcoma of the mandible: a case report.下颌骨骨内横纹肌肉瘤:一例报告。
Int J Surg Pathol. 2003 Jan;11(1):57-60. doi: 10.1177/106689690301100115.