Carvalho Giovanna Lopes, Heguedusch Daniele, Pellizzon Antônio Cássio Assis, Lira Renan Bezerra, Alves Fábio Abreu, Jaguar Graziella Chagas
A.C. Camargo Cancer Center Departamento de Estomatologia São PauloSP Brasil A.C. Camargo Cancer Center, Departamento de Estomatologia, São Paulo, SP, Brasil.
A. C. Camargo Cancer Center Departamento de Radioterapia São Paulo Brasil A. C. Camargo Cancer Center, Departamento de Radioterapia, São Paulo, Brasil.
Autops Case Rep. 2022 Jul 22;12:e2021389. doi: 10.4322/acr.2021.389. eCollection 2022.
Nasopharyngeal carcinoma (NPC) is a malignant tumor rarely found in the head and neck, representing about 1% of all malignancies. The main treatment for NPC is radiation therapy, which is often given in combination with chemotherapy. However, such treatment may lead to long-term complications, including second primary tumors (SPTs) and osteoradionecrosis (ORN). Both complications have similar radiological characteristics, which can lead to erroneous diagnoses. This paper describes a case of a second primary tumor in a patient after 20 years of radiotherapy in the area where a previous extraction was performed, mimicking an osteoradionecrosis process.
鼻咽癌（NPC）是一种在头颈部罕见的恶性肿瘤，约占所有恶性肿瘤的1%。鼻咽癌的主要治疗方法是放射治疗，通常与化疗联合使用。然而，这种治疗可能会导致长期并发症，包括第二原发性肿瘤（SPT）和放射性骨坏死（ORN）。这两种并发症具有相似的放射学特征，可能导致误诊。本文描述了一例患者在先前拔牙区域接受20年放射治疗后发生第二原发性肿瘤的病例，该病例酷似放射性骨坏死过程。
