Worrall Emily B, Chhaparia Anuj, Carpenter Danielle, Neuschwander-Tetri Brent A
Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO.
Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, Saint Louis, MO.
ACG Case Rep J. 2022 Aug 31;9(8):e00846. doi: 10.14309/crj.0000000000000846. eCollection 2022 Aug.
We describe a patient who presented with hematemesis and was found to have unusually well-demarcated erythematous mucosa with a 2-3 cm irregular nonbleeding necrotic ulcer in the gastric body on esophagogastroduodenoscopy. Biopsy and pathologic examination of the tissue indicated infection with a rare bacterium, , prompting treatment with an unproven combination of 4 agents: metronidazole, ciprofloxacin, sucralfate, and pantoprazole. Repeat esophagogastroduodenoscopy 8 weeks later revealed complete resolution of the ulceration and surrounding erythema. These results may contribute toward establishing an appropriate therapeutic regimen for future infections.
我们描述了一名出现呕血症状的患者,在食管胃十二指肠镜检查中发现其胃体部有界限异常清晰的红斑性黏膜,伴有一个2 - 3厘米不规则的非出血性坏死溃疡。对该组织进行活检和病理检查显示感染了一种罕见细菌,这促使采用一种未经证实的四联药物组合进行治疗:甲硝唑、环丙沙星、硫糖铝和泮托拉唑。8周后复查食管胃十二指肠镜检查发现溃疡及周围红斑完全消退。这些结果可能有助于为未来的[细菌名称未给出]感染建立合适的治疗方案。