Siddiqui Suhail Sarwar, Dominic Nibu, Kumar Sukriti, Usman Kauser, Saran Sai, Agrawal Avinash, Gurjar Mohan, Muzaffar Syed Nabeel
Department of Critical Care Medicine, King George Medical University, Lucknow, Uttar Pradesh, India.
Department of Endocrinology, Aster Medcity, Kochi, Kerala, India.
J Crit Care Med (Targu Mures). 2022 Aug 12;8(3):214-222. doi: 10.2478/jccm-2022-0018. eCollection 2022 Jul.
Sheehan's syndrome is a life-threatening endocrine emergency seen in postpartum females secondary to ischemic pituitary necrosis. It is a frequent cause of hypopituitarism in developing countries that occurs secondary to postpartum haemorrhage (PPH). Patients with Sheehan's syndrome often present with organ dysfunctions in critical care settings, secondary to stressors precipitating the underlying hormonal deficiencies. The initial clinical picture of Sheehan's syndrome may mimic some other disease, leading to misdiagnosis and diagnostic delay. Strict vigilance, timely diagnosis, and appropriate management are essential to avoid diagnostic delay and to improve the patient outcome. In this case series, we describe 5 cases of previously undiagnosed Sheehan's syndrome (including young, middle aged and postmenopausal females) that presented to critical care and emergency settings with organ failures.
席汉综合征是一种危及生命的内分泌急症，见于产后女性，继发于缺血性垂体坏死。在发展中国家，它是继发于产后出血（PPH）的垂体功能减退的常见原因。席汉综合征患者在重症监护环境中常因诱发潜在激素缺乏的应激因素而出现器官功能障碍。席汉综合征的初始临床表现可能与其他一些疾病相似，导致误诊和诊断延迟。严格的警惕、及时的诊断和适当的管理对于避免诊断延迟和改善患者预后至关重要。在本病例系列中，我们描述了5例先前未诊断出的席汉综合征病例（包括年轻、中年和绝经后女性），这些患者因器官衰竭而被送往重症监护和急诊科室。
