Sun Hong, Wang Weiqun, Zhang Shouyuan, Lin Chenglei
Department of Pediatrics, Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine, Hangzhou, Zhejiang 310003, China.
Evid Based Complement Alternat Med. 2022 Aug 25;2022:8325756. doi: 10.1155/2022/8325756. eCollection 2022.
To observe the correlation between nutritional status, bone age, and sexual development in children and adolescents.
895 children and adolescents who underwent physical examination in the growth and development clinic and height clinic of our hospital from 2019 to 2021 were selected as the research objects. The subjects were divided into emaciation group, normal group, overweight group, and obesity group. The bone age level, bone age assessment, sexual development, and early maturity rate of each group were compared.
The bone age difference (BAD) of the overweight and obesity groups was higher than that of the normal group, and the BAD of the obesity group was higher than that of the emaciation group ( < 0.05). Compared with the normal group, the risk of advancement of bone age in the overweight group increased by 2.674 times (male) and 1.908 times (female), the risk of advancement of bone age in the obesity group increased by 6.376 times (male) and 14.687 times (female), the risk of retardation of bone age in the emaciation group increased by 2.150 times (male) and 3.092 times (female). Whether it was male or female, the sexual development of overweight and obese was higher than that of the normal weight group in the same age group. Among female children, the sexual precocious puberty rate of the overweight + obesity group is higher.
The nutritional status of children and adolescents is closely related to their bone age and sexual development.
观察儿童青少年营养状况、骨龄与性发育之间的相关性。
选取2019年至2021年在我院生长发育门诊及身高门诊进行体格检查的895名儿童青少年作为研究对象。将受试者分为消瘦组、正常组、超重组和肥胖组。比较各组的骨龄水平、骨龄评估、性发育及早熟率。
超重和肥胖组的骨龄差值(BAD)高于正常组,肥胖组的BAD高于消瘦组(<0.05)。与正常组相比,超重组骨龄提前风险男性增加2.674倍、女性增加1.908倍,肥胖组骨龄提前风险男性增加6.376倍、女性增加14.687倍,消瘦组骨龄落后风险男性增加2.150倍、女性增加3.092倍。无论男性还是女性,超重和肥胖者的性发育均高于同年龄组正常体重者。在女童中,超重+肥胖组的性早熟率更高。
儿童青少年的营养状况与其骨龄和性发育密切相关。