Department of Dermatology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
Department of Pediatrics, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
Pediatr Dermatol. 2022 Nov;39(6):1005-1006. doi: 10.1111/pde.15126. Epub 2022 Sep 5.
Dominant dystrophic epidermolysis bullosa (DDEB), an inherited disorder due to type VII collagen mutations, is characterized by blisters and erosions that heal with scarring, atrophy, and milia. There is no established role for laser in the management of patients with DDEB. Pulsed dye laser (PDL) is most often used to target vascular skin lesions. We describe a patient with DDEB with marked improvement in erythema as well as fewer and less symptomatic episodes of blistering following treatment with PDL.
显性营养不良型大疱性表皮松解症（DDEB）是一种遗传性疾病，由 VII 型胶原基因突变引起，其特征是水疱和糜烂，愈合后会留下瘢痕、萎缩和粟丘疹。激光在 DDEB 患者的治疗中没有明确的作用。脉冲染料激光（PDL）最常用于治疗血管性皮肤病变。我们描述了一例 DDEB 患者，在接受 PDL 治疗后，红斑明显改善，水疱发作次数减少，症状减轻。
