• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Looking at IGF-1 through the hourglass.

作者信息

Zhang William B, Milman Sofiya

机构信息

Physician-Scientist Development Program, Department of Pathology, University of Chicago, Chicago, IL 60637, USA.

Department of Medicine and Genetics, Institute for Aging Research, Albert Einstein College of Medicine, Bronx 10461, NY.

出版信息

Aging (Albany NY). 2022 Aug 25;14(16):6379-6380. doi: 10.18632/aging.204257.

DOI:10.18632/aging.204257
PMID:36063137
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9467390/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0142/9467390/1906b48d763c/aging-14-204257-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0142/9467390/1906b48d763c/aging-14-204257-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0142/9467390/1906b48d763c/aging-14-204257-g001.jpg

相似文献

1
Looking at IGF-1 through the hourglass.透过沙漏看胰岛素样生长因子-1。
Aging (Albany NY). 2022 Aug 25;14(16):6379-6380. doi: 10.18632/aging.204257.
2
Mechanisms of thyroid hormone action on the insulin-like growth factor system: all thyroid hormone effects are not growth hormone mediated.甲状腺激素对胰岛素样生长因子系统的作用机制：并非所有甲状腺激素的作用都由生长激素介导。
Endocrinology. 1993 Feb;132(2):781-8. doi: 10.1210/endo.132.2.7678799.
3
Models of growth hormone and IGF-1 deficiency: applications to studies of aging processes and life-span determination.生长激素和胰岛素样生长因子-1缺乏模型：在衰老过程研究和寿命测定中的应用。
J Gerontol A Biol Sci Med Sci. 2002 May;57(5):B177-88. doi: 10.1093/gerona/57.5.b177.
4
Insulin-like growth factors and aging.胰岛素样生长因子与衰老
Endocrinol Metab Clin North Am. 1987 Dec;16(4):995-1011.
5
Growth hormone and insulin-like growth factor-1 (IGF-1) and their influence on cognitive aging.生长激素和胰岛素样生长因子-1（IGF-1）及其对认知衰老的影响。
Ageing Res Rev. 2005 May;4(2):195-212. doi: 10.1016/j.arr.2005.02.001.
6
A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan.对生长激素和胰岛素样生长因子-1在衰老和寿命中的作用的批判性分析。
Trends Genet. 2002 Jun;18(6):295-301. doi: 10.1016/S0168-9525(02)02696-3.
7
Growth hormone, insulin-like growth factor-1 and the aging brain.生长激素、胰岛素样生长因子-1与衰老大脑
Exp Gerontol. 2015 Aug;68:76-81. doi: 10.1016/j.exger.2014.10.002. Epub 2014 Oct 7.
8
Regulation of the growth hormone-insulin-like growth factor I axis in developing and adult monkeys is affected by estradiol replacement and supplementation with insulin-like growth factor I.在发育中和成年猴子中，生长激素-胰岛素样生长因子I轴的调节受到雌二醇替代和胰岛素样生长因子I补充的影响。
J Clin Endocrinol Metab. 1998 Jun;83(6):2018-28. doi: 10.1210/jcem.83.6.4872.
9
The immune-endocrine loop during aging: role of growth hormone and insulin-like growth factor-I.衰老过程中的免疫-内分泌循环：生长激素和胰岛素样生长因子-I的作用
Neuroimmunomodulation. 1999 Jan-Apr;6(1-2):56-68. doi: 10.1159/000026365.
10
Effect of aging on growth hormone-induced insulin-like growth factor-I secretion from cultured rat chondrocytes.衰老对培养的大鼠软骨细胞生长激素诱导的胰岛素样生长因子-I分泌的影响。
Growth Horm IGF Res. 1998 Oct;8(5):403-9. doi: 10.1016/s1096-6374(98)80311-0.

引用本文的文献

1
Progression in the In Vitro Macrophage Expansion.体外巨噬细胞扩增的进展
J Immunol Res. 2025 Apr 28;2025:9994439. doi: 10.1155/jimr/9994439. eCollection 2025.
2
The neurobiology of insulin-like growth factor I: From neuroprotection to modulation of brain states.胰岛素样生长因子I的神经生物学：从神经保护到脑状态调节。
Mol Psychiatry. 2023 Aug;28(8):3220-3230. doi: 10.1038/s41380-023-02136-6. Epub 2023 Jun 23.

本文引用的文献

1
The antagonistic pleiotropy of insulin-like growth factor 1.胰岛素样生长因子 1 的拮抗多效性。
Aging Cell. 2021 Sep;20(9):e13443. doi: 10.1111/acel.13443. Epub 2021 Aug 7.
2
Insulin-like Growth Factor-1 and IGF Binding Proteins Predict All-Cause Mortality and Morbidity in Older Adults.胰岛素样生长因子-1 和 IGF 结合蛋白可预测老年人的全因死亡率和发病率。
Cells. 2020 Jun 1;9(6):1368. doi: 10.3390/cells9061368.
3
Structural absorption by barbule microstructures of super black bird of paradise feathers.超级天堂鸟羽毛羽小枝微结构的结构吸收
Nat Commun. 2018 Jan 9;9(1):1. doi: 10.1038/s41467-017-02088-w.
4
The Somatotropic Axis in Human Aging: Framework for the Current State of Knowledge and Future Research.人类衰老过程中的生长激素轴：当前知识现状与未来研究框架
Cell Metab. 2016 Jun 14;23(6):980-989. doi: 10.1016/j.cmet.2016.05.014.
5
Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity.低胰岛素样生长因子-1水平可预测人类超长寿命者的生存情况。
Aging Cell. 2014 Aug;13(4):769-71. doi: 10.1111/acel.12213. Epub 2014 Mar 12.
6
Both low and high serum IGF-I levels associate with cancer mortality in older men.低和高血清 IGF-I 水平与老年男性的癌症死亡率相关。
J Clin Endocrinol Metab. 2012 Dec;97(12):4623-30. doi: 10.1210/jc.2012-2329. Epub 2012 Sep 26.
7
IGF1 molecular anomalies demonstrate its critical role in fetal, postnatal growth and brain development.IGF1 分子异常表明其在胎儿、出生后生长和大脑发育中具有关键作用。
Best Pract Res Clin Endocrinol Metab. 2011 Feb;25(1):181-90. doi: 10.1016/j.beem.2010.08.005.
8
Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity.胰岛素/胰岛素样生长因子1信号通路中的常见基因变异与人类长寿的关联。
Aging Cell. 2009 Aug;8(4):460-72. doi: 10.1111/j.1474-9726.2009.00493.x. Epub 2009 May 31.