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[正常及各种病理状态下关节软骨的嗜碱性线]

[Basophilic line of the articular cartilage in normal and various pathological states].

作者信息

Gongadze L R

出版信息

Arkh Anat Gistol Embriol. 1987 Apr;92(4):52-7.

PMID:3606408
Abstract

Epiphyses of long tubular bones in the man and animals of various age, as well as experimental material of the adjuvant arthritis, with special reference to the basal part of the articular cartilage have been studied by means of histological, histochemical and histometrical methods. The structural-chemical organization of the basophilic line (tidemark) of the articular cartilage ensures its barrier role and participation in regulating selective permeability. Reconstruction of the tidemark in the process of physiological ageing and in cases of the articular pathology is aimed to preserve its integrity and in this way a complete differentiation of the noncalcified and calcified structures is secured. Disturbance of the basophilic line results in changes of the articular selective permeability, in invasion of vessels and structural elements of the bone marrow, and in development of profound distrophic and destructive changes of the cartilage--in deforming artrosis. Deflations in the structural-chemical organization of the tidemark indicate certain disturbances in the state of the system articular cartilage--subchondral bone. These data can be of prognostic importance.

摘要

采用组织学、组织化学和组织计量学方法,对不同年龄男性和动物长管状骨的骨骺,以及佐剂性关节炎的实验材料进行了研究,特别关注关节软骨的基部。关节软骨嗜碱性线(潮标)的结构化学组织确保了其屏障作用,并参与调节选择性通透性。在生理老化过程和关节病理情况下,潮标的重建旨在保持其完整性,从而确保非钙化和钙化结构的完全分化。嗜碱性线的紊乱会导致关节选择性通透性的改变、骨髓血管和结构成分的侵入,以及软骨深层营养不良和破坏性变化的发展——在变形性关节炎中。潮标结构化学组织的缺陷表明关节软骨 - 软骨下骨系统状态存在某些紊乱。这些数据可能具有预后意义。

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