Bipolar and Depressive Disorders Unit, Hospital Clinic, Institute of Neurosciences, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain.
Department of Affective Disorders, Aarhus University Hospital-Psychiatry, Aarhus, Denmark.
Bipolar Disord. 2022 Dec;24(8):817-825. doi: 10.1111/bdi.13254. Epub 2022 Sep 25.
The use of electroconvulsive therapy (ECT) in the treatment of bipolar disorder (BD) remains poorly described. Based on data from Danish registries with complete nationwide coverage, this study of patients with incident BD aimed to describe when, how, and for whom ECT is used in the context of BD.
We identified patients receiving their first diagnosis of BD in the period from 2008 to 2018, who subsequently received ECT. Descriptive statistics were used to clarify when, how, and for whom ECT is used.
We identified 1338 patients with incident BD who subsequently received ECT. The median age at the first ECT session was 50.6 years (interquartile range [IQR]: 26.4), and 62% of those treated with ECT were female. The median time from the diagnosis of BD to the first ECT treatment was 0.6 years (IQR: 2.6), and 58% of the patients receiving ECT had the first treatment within the first year after being diagnosed with BD. The most common indication for the first ECT treatment was depression (mainly non-psychotic depression), followed by mania (mainly psychotic mania). The first ECT session was typically provided to inpatients (97%), upon patient consent (98%) and with bilateral electrode placement (60%).
A substantial proportion of the patients with incident BD who receive ECT require this treatment within the first year after the diagnosis. The most common indication for ECT is depression followed by (psychotic) mania. Inpatient voluntary ECT using bilateral electrode placement is the most common form of administration.
电抽搐疗法（ECT）在双相障碍（BD）治疗中的应用描述仍不完善。本研究基于丹麦具有完整全国覆盖范围的登记处数据，旨在描述 BD 患者ECT 的使用时间、方式和对象。
我们确定了 2008 年至 2018 年间首次诊断为 BD 并随后接受 ECT 的患者。使用描述性统计来阐明 ECT 的使用时间、方式和对象。
我们确定了 1338 例首次诊断为 BD 后接受 ECT 的患者。首次 ECT 治疗时的中位年龄为 50.6 岁（四分位距 [IQR]：26.4），接受 ECT 治疗的患者中有 62%为女性。从 BD 诊断到首次 ECT 治疗的中位时间为 0.6 年（IQR：2.6），接受 ECT 的患者中有 58%在诊断后一年内接受首次治疗。首次 ECT 治疗的最常见适应症是抑郁症（主要是非精神病性抑郁症），其次是躁狂症（主要是精神病性躁狂症）。首次 ECT 治疗通常提供给住院患者（97%），获得患者同意（98%）并采用双侧电极放置（60%）。
相当一部分接受 ECT 的新发 BD 患者需要在诊断后一年内接受此治疗。ECT 的最常见适应症是抑郁症，其次是（精神病性）躁狂症。采用双侧电极放置的住院自愿 ECT 是最常见的治疗方式。
