Meredith T A
Arch Ophthalmol. 1987 Jul;105(7):949-53. doi: 10.1001/archopht.1987.01060070085034.
Four generations of a family with an unusual pattern of ocular vascular abnormalities were studied. Two male and three female members in two affected generations demonstrated prominent retinal venous segmental beading. Various individuals demonstrated areas of focal retinal infarction, surface retinal neovascularization, vitreous hemorrhage, microaneurysm formation, altered vascular permeability with lipid exudation, and focal edema. Several members demonstrated abnormalities of distribution of arterioles and venules. Saccular aneurysmal changes were present in conjunctival vessels. Renal disease was present in two affected individuals in the fourth and fifth decades, respectively.
对一个有着不同寻常眼部血管异常模式的家族的四代人进行了研究。在两个患病代中，两名男性和三名女性成员表现出明显的视网膜静脉节段性串珠样改变。不同个体出现了局灶性视网膜梗死区域、视网膜表面新生血管形成、玻璃体积血、微动脉瘤形成、伴有脂质渗出的血管通透性改变以及局灶性水肿。几名成员表现出小动脉和小静脉分布异常。结膜血管存在囊状动脉瘤样改变。肾病分别出现在第四和第五个十年的两名患病个体中。
