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南澳大利亚州主要公立医院的医院获得性并发症。

Hospital Acquired Complications in South Australian major public hospitals.

机构信息

Intensive & Critical Care, 14351Flinders Medical Centre, Adelaide, Australia.

Eastern Health Intensive Care Research, Box Hill & Maroondah & Angliss Hospitals, Melbourne, Australia.

出版信息

Anaesth Intensive Care. 2022 Nov;50(6):468-475. doi: 10.1177/0310057X221092460. Epub 2022 Sep 5.

Abstract

The prevalence of Hospital Acquired Complications (HACs) within major hospitals and intensive care units (ICUs) is often used as an indication of care quality. We performed a retrospective cohort study of acute care separations from four adult public hospitals in the state of South Australia, Australia. Data were derived from the Integrated South Australian Activity Collection (ISAAC) database, subdivided into those admitted to ICU or non-ICU (Ward) in tertiary referral or (other major) metropolitan hospitals. During the five-year study period (1 July 2013 to 30 June 2018), there were 471,934 adult separations with 65,133 HAC events reported in 43,987 (9.32%) at a mean rate of 13.8 (95% confidence interval (CI) 13.7 to 13.9) HAC events per 100 separations and 18.5 (95% CI 18.4 to 18.7) per 1000 bed days. The Ward cohort accounted for the majority (430,583 (91.2%)) of separations, in-hospital deaths (6928 (66.4%)) and HAC events (29,826 (67.8%)). The smaller ICU cohort (41,351 (8.76%)) had a higher mortality rate (8.46% versus 1.61%;  < 0.001), longer length of stay (median 10.0 (interquartile range (IQR) 6.0-18.0) days versus 4.0 (IQR 3.0-8.0) days  < 0.001), and higher HAC prevalence (62.1 (95% CI 61.3 to 62.9) versus 9.16 (95% CI 9.07 to 9.25) per 100 separations  < 0.001). Both ICU and Ward HAC prevalence rates were higher in tertiary referral than major metropolitan hospitals ( < 0.001). In conclusion, higher HAC prevalence rates in the ICU and tertiary referral cohorts may be due to high-risk patient cohorts, variable provision of care, or both, and warrants urgent clinical investigation and further research.

摘要

医院获得性并发症(HACs)在大型医院和重症监护病房(ICU)中的发生率通常被用作护理质量的指标。我们对澳大利亚南澳大利亚州四家公立医院的急性护理分离患者进行了回顾性队列研究。数据来自综合南澳大利亚活动采集(ISAAC)数据库,分为 ICU 或非 ICU(病房)入院的患者,这些患者在三级转诊或(其他主要)大都市医院接受治疗。在五年的研究期间(2013 年 7 月 1 日至 2018 年 6 月 30 日),有 471934 例成人分离患者,其中 65133 例发生 HAC 事件,占 43987 例(9.32%),发生率为每 100 例分离患者 13.8(95%置信区间(CI)为 13.7 至 13.9)例 HAC 事件和每 1000 个床位日 18.5(95%CI 为 18.4 至 18.7)例 HAC 事件。病房队列占大多数(430583 例(91.2%)),包括住院死亡(6928 例(66.4%))和 HAC 事件(29826 例(67.8%))。较小的 ICU 队列(41351 例(8.76%))死亡率较高(8.46%对 1.61%;<0.001),住院时间较长(中位数 10.0(四分位距(IQR)6.0-18.0)天对 4.0(IQR 3.0-8.0)天<0.001),HAC 发生率较高(62.1(95%CI 61.3 至 62.9)对 9.16(95%CI 9.07 至 9.25)/100 例分离患者<0.001)。ICU 和病房的 HAC 发生率在三级转诊医院均高于主要大都市医院(<0.001)。总之,ICU 和三级转诊队列中较高的 HAC 发生率可能是由于高危患者群体、护理提供的差异,或两者兼而有之,这需要紧急临床调查和进一步研究。

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